国际呼吸杂志
國際呼吸雜誌
국제호흡잡지
INTERNATIONAL JOURNAL OF RESPIRATION
2015年
4期
270-273
,共4页
唐纯丽%罗群%谢佳星%区泳儿%陈荣昌
唐純麗%囉群%謝佳星%區泳兒%陳榮昌
당순려%라군%사가성%구영인%진영창
间质性肺疾病%肺栓塞%临床特征
間質性肺疾病%肺栓塞%臨床特徵
간질성폐질병%폐전새%림상특정
Interstitial lung disease%Pulmonary embolism%Clinical features
目的：探讨分析间质性肺疾病(ILD)合并肺栓塞(PE)患者的临床特征。方法收集2011年1月至2011 年 12月期间在广州呼吸疾病研究所住院治疗的12例 ILD 并发 PE 的患者为 ILD 合并PE 组,并募集同期24例性别、年龄相匹配的 PE 患者作为对照,即单纯 PE 组,比较两组病例的身高、体质量、既往病史、近期制动或手术、吸烟、糖皮质激素使用等特征,咯血、胸痛、呼吸困难、心悸、下肢浮肿等症状,以及 D-二聚体、动脉血气分析、肺动脉收缩压、PE 类型(大面积和非大面积)等实验室检查。结果与单纯 PE 组相比,ILD 合并 PE 组糖皮质激素应用史(50.0% vs 12.5%)、咳嗽(100.0% vs 70.8%)、心悸(41.7% vs 8.3%)比例更高,动 脉血气分析 提 示 PaO 2下降更明显[(63.14±12.94)mmHg vs (73.05±14.67)mmHg]。两组在基础疾病、咯血、胸痛、呼吸困难、下肢浮肿、血常规、D-二聚体、肺动脉收缩压及 PE 的类型差异无统计学意义,12例 ILD 合并 PE 的患者都为非大面积 PE。结论 ILD 合并 PE 组患者糖皮质激素应用及咳嗽、心悸等症状发生率高,动脉血气 PaO 2下降更明显,对 ILD 合并 PE 可能有提示作用。
目的：探討分析間質性肺疾病(ILD)閤併肺栓塞(PE)患者的臨床特徵。方法收集2011年1月至2011 年 12月期間在廣州呼吸疾病研究所住院治療的12例 ILD 併髮 PE 的患者為 ILD 閤併PE 組,併募集同期24例性彆、年齡相匹配的 PE 患者作為對照,即單純 PE 組,比較兩組病例的身高、體質量、既往病史、近期製動或手術、吸煙、糖皮質激素使用等特徵,咯血、胸痛、呼吸睏難、心悸、下肢浮腫等癥狀,以及 D-二聚體、動脈血氣分析、肺動脈收縮壓、PE 類型(大麵積和非大麵積)等實驗室檢查。結果與單純 PE 組相比,ILD 閤併 PE 組糖皮質激素應用史(50.0% vs 12.5%)、咳嗽(100.0% vs 70.8%)、心悸(41.7% vs 8.3%)比例更高,動 脈血氣分析 提 示 PaO 2下降更明顯[(63.14±12.94)mmHg vs (73.05±14.67)mmHg]。兩組在基礎疾病、咯血、胸痛、呼吸睏難、下肢浮腫、血常規、D-二聚體、肺動脈收縮壓及 PE 的類型差異無統計學意義,12例 ILD 閤併 PE 的患者都為非大麵積 PE。結論 ILD 閤併 PE 組患者糖皮質激素應用及咳嗽、心悸等癥狀髮生率高,動脈血氣 PaO 2下降更明顯,對 ILD 閤併 PE 可能有提示作用。
목적：탐토분석간질성폐질병(ILD)합병폐전새(PE)환자적림상특정。방법수집2011년1월지2011 년 12월기간재엄주호흡질병연구소주원치료적12례 ILD 병발 PE 적환자위 ILD 합병PE 조,병모집동기24례성별、년령상필배적 PE 환자작위대조,즉단순 PE 조,비교량조병례적신고、체질량、기왕병사、근기제동혹수술、흡연、당피질격소사용등특정,각혈、흉통、호흡곤난、심계、하지부종등증상,이급 D-이취체、동맥혈기분석、폐동맥수축압、PE 류형(대면적화비대면적)등실험실검사。결과여단순 PE 조상비,ILD 합병 PE 조당피질격소응용사(50.0% vs 12.5%)、해수(100.0% vs 70.8%)、심계(41.7% vs 8.3%)비례경고,동 맥혈기분석 제 시 PaO 2하강경명현[(63.14±12.94)mmHg vs (73.05±14.67)mmHg]。량조재기출질병、각혈、흉통、호흡곤난、하지부종、혈상규、D-이취체、폐동맥수축압급 PE 적류형차이무통계학의의,12례 ILD 합병 PE 적환자도위비대면적 PE。결론 ILD 합병 PE 조환자당피질격소응용급해수、심계등증상발생솔고,동맥혈기 PaO 2하강경명현,대 ILD 합병 PE 가능유제시작용。
Objective To analysis the clinical features of patients with interstitial lung disease complicated by pulmonary embolism (ILD-PE).Methods Twelve cases of ILD-PE and 24 cases of PE as the control group were recruited from January 201 1 to December 201 1 in the Guangzhou Institute of Respiratory Diseases.Height,body mass,past medical history,recent braking or operation,smoking, glucocorticoid use,symptoms such as hemoptysis,chest pain,dyspnea,heart palpitations,lower extremity edema,and D-dimer,arterial blood gas analysis,pulmonary artery systolic pressure,type of PE (large area and non massive) were compared between two groups.Results Compared with control group,the incidence of cough (100.0% vs 70.8%),palpitations (41.7% vs 8.3%),application of glucocorticoid (50.0% vs 12.5%)in ILD-PE group was higher.There was no significant difference in underlying disease,hemoptysis,chest pain,dyspnea,lower extremity edema,D-dimer,pulmonary artery systolic pressure,and type of PE between two groups.All 12 cases of ILD-PE were non-massive PE.Conclusions In ILD-PE patients,the incidence of cough,palpitations,and glucocorticoid use is higher,PaO2 significantly decreases,which suggests that ILD is complicated by PE.
