CAJ | 학술논문

目的探析老年冠心病患者胃癌根治术中七氟醚与丙泊酚麻醉的心肌保护作用.方法入选2013年3月至2014年3月我院冠心病合并胃癌老年患者86例,所有患者均进行胃癌根治术,按麻醉方式的不同分为实验组和对照组,实验组进行七氟醚复合瑞芬太尼麻醉,对照组进行丙泊酚复合瑞芬太尼麻醉,比较两组患者不同时间点的血清肌酸激酶同工酶(CK-MB)及血清心肌肌钙蛋白Ⅰ(cTnⅠ)水平.结果实验组患者术后6、12、24 h的CK-MB、cTnⅠ水平显著低于对照组,差异有统计学意义(P＜0.01).结论老年冠心病患者胃癌根治术进行七氟醚与瑞芬太尼复合麻醉保护心肌效果更强,值得临床推广.
목적 탐석노년관심병환자위암근치술중칠불미여병박분마취적심기보호작용.방법 입선2013년3월지2014년3월아원관심병합병위암노년환자86례,소유환자균진행위암근치술,안마취방식적불동분위실험조화대조조,실험조진행칠불미복합서분태니마취,대조조진행병박분복합서분태니마취,비교량조환자불동시간점적혈청기산격매동공매(CK-MB)급혈청심기기개단백Ⅰ(cTnⅠ)수평.결과 실험조환자술후6、12、24 h적CK-MB、cTnⅠ수평현저저우대조조,차이유통계학의의(P＜0.01).결론 노년관심병환자위암근치술진행칠불미여서분태니복합마취보호심기효과경강,치득림상추엄.
Objective To compare cardioprotective effect of sevoflurane and propofol anesthesia in elderly patients with coronary heart disease during radical gastrectomy.Methods 86 elderly patients with gastric cancer and coronary heart disease were selected in our hospital from March 2013 to March 2014.All patients underwent radical gastrectomy,and were divided into experimental group and control group according to different anesthesia methods.Experimental group underwent sevoflurane combined with remifentanil anesthesia,while control group underwent propofol combined with remifentanil anesthesia.Compared levels of serum creatine kinase isoenzyme (CK-MB) and cardiac troponin Ⅰ (cTnⅠ) at different time points of two groups.Result The levels of CK-MB,cTnⅠ 6,12,24 hours after operation in experimental group were significantly lower than those in control group,with statistically significant differences (P＜0.01).Conclusion Cardioprotective effect of sevoflurane combined with remifentanil anesthesia is much stronger in elderly patients with coronary heart disease during radical gastrectomy,worthy of clinical promotion.