CAJ | 학술논문

目的通过对我院剖宫产手术患者围手术期使用抗菌药物的分析,了解剖宫产围手术期预防应用抗菌药的情况,促进临床合理用药.方法采用回顾性调查方法,随机抽取我院2012年6月至2013年6月产科剖宫产手术出院病历.对剖宫产围手术期抗菌药物的用药品种、频率、时间、联合用药等情况进行分析.结果 243例剖宫产病例全部使用抗菌药物,使用频率最高的抗菌药物是头孢西丁、头孢唑林.用药持续时间≤48 h有203例(83.5％),用药时间49 ～ 72 h有10例(4.1％),用药时间＞ 72h有30例(12.4％).联合用药主要包括头孢西丁+奥硝唑、头孢唑啉钠+甲硝唑.结论我院剖宫产患者围手术期抗菌药物的使用基本按照卫生部于2009年3月发布的《卫生部办公厅关于抗菌药物临床应用管理有关问题的通知》(简称38号文件)执行,但仍然存在一些不合理处,主要表现在用药持续时间和药物联合用药的选择方面,医院应该进一步加强围手术期抗菌药物的使用管理.
목적 통과대아원부궁산수술환자위수술기사용항균약물적분석,료해부궁산위수술기예방응용항균약적정황,촉진림상합리용약.방법 채용회고성조사방법,수궤추취아원2012년6월지2013년6월산과부궁산수술출원병력.대부궁산위수술기항균약물적용약품충、빈솔、시간、연합용약등정황진행분석.결과 243례부궁산병례전부사용항균약물,사용빈솔최고적항균약물시두포서정、두포서림.용약지속시간≤48 h유203례(83.5％),용약시간49 ～ 72 h유10례(4.1％),용약시간＞ 72h유30례(12.4％).연합용약주요포괄두포서정+오초서、두포서람납+갑초서.결론 아원부궁산환자위수술기항균약물적사용기본안조위생부우2009년3월발포적《위생부판공청관우항균약물림상응용관리유관문제적통지》(간칭38호문건)집행,단잉연존재일사불합리처,주요표현재용약지속시간화약물연합용약적선택방면,의원응해진일보가강위수술기항균약물적사용관리.
Objective By analyzing antibiotics application in cesarean section in our hospital,to investigate the prophylactic use of antibiotics in women undergoing cesarean section.Methods Women undergoing cesarean section in obstetrics of our hospital from June 2012 to June 2013 were randomly selected.Medication species,frequency,time,and drug combination of perioperative antibiotics application were analyzed.Results Antibiotics were used in all of the 243 cases of cesarean section.The most frequently used antibiotics were cefoxitin and cefazolin.Duration of drug usage in 203 cases was ≤ 48 h,10 cases 49-72 h,30 cases ＞72 h.Drug combination included cefoxitin + ornidazole and cefazolin + metronidazole.Conclusions Antibiotics application during perioperative period of cesarean section in our hospital were in accordance with No.38 document published by Ministry of Public Health in March 2009,but there were still some unreasonable problems,which were mostly duration of drug usage and selection of drug combination.Management ofperioperative antibiotics application should be further strengthened.