CAJ | 학술논문

目的：通过针对原发性高血压人群中国亚临床靶器官受损与肥胖的关系进分析。方法选择我院收治的高血压并伴肥胖患者122例，为观察组，单纯高血压患者110例，为对照组，以评估两组患者尿微量白蛋白/肌酐比值、颈动脉粥样硬化与肥胖、高血压的相关性。结果观察组患者出现尿微量白蛋白与颈动脉粥样硬化比例为23.77％与74.59％，大于对照组的13.64％与71.82％，P＜0.05，差异具有统计学意义，BMI是影响尿微量白蛋白（β=0.159，P＜0.0001）和颈动脉粥样硬化（β=0.129，P＜0.01）的主要因素。结论伴肥胖的高血压患者亚临床靶器官受损的发生率更高，临床上应积极防治。
목적：통과침대원발성고혈압인군중국아림상파기관수손여비반적관계진분석。방법선택아원수치적고혈압병반비반환자122례，위관찰조，단순고혈압환자110례，위대조조，이평고량조환자뇨미량백단백/기항비치、경동맥죽양경화여비반、고혈압적상관성。결과관찰조환자출현뇨미량백단백여경동맥죽양경화비례위23.77％여74.59％，대우대조조적13.64％여71.82％，P＜0.05，차이구유통계학의의，BMI시영향뇨미량백단백（β=0.159，P＜0.0001）화경동맥죽양경화（β=0.129，P＜0.01）적주요인소。결론반비반적고혈압환자아림상파기관수손적발생솔경고，림상상응적겁방치。
Objective To study the relationship between subclinical target organ damage and obesity in Chinese population of primary hypertension. MethodsSelected 122 patients with hypertension and obesity as the observation group in our hospital, 110 cases of hypertension patients as control group, to evaluate the correlation of trace between the ratio of albumin to creatinine and carotid atherosclerosis with obesity and hypertension.Results Observation group emergence of microalbuminuria and carotid atherosclerosis respectively in the ratio of 23.77% and 74.59%,it was signiifcantly higher than control group that of 13.64% and 71.82%(P<0.05), the difference had statistical signiifcance, BMI is the main factors effect of urinary microalbumin (β=0.159,P<0.0001) and carotid artery atherosclerosis (β=0.129,P<0.01).Conclusion The obese hypertensive patients with subclinical target organ damage occurrence rate is higher, clinical should actively control.