中国骨质疏松杂志
中國骨質疏鬆雜誌
중국골질소송잡지
CHINESE JOURNAL OF OSTEOPOROSIS
2015年
4期
421-423
,共3页
骨质疏松%骨密度%骨折发生率
骨質疏鬆%骨密度%骨摺髮生率
골질소송%골밀도%골절발생솔
Osteoporosis%Bone mineral density%Fracture incidence
目的:通过对132例原发性骨质疏松症患者抗骨质疏松规范治疗1年前后的对比,明确骨质疏松症早期诊断治疗的意义。方法以我院2011-2012年间门诊诊治的有完整记录的原发性骨质疏松症患者132例为研究对象,给予正规抗骨质疏松治疗1年,对治疗前后每位患者的临床症状[视觉模拟评分( Visual Analogue Score,VAS),双能X线吸取测量法( Dual Energy X-ray Absorptiometry,DEXA)测定骨密度(Bone mineral density,BMD)]、骨折发生率进行对比和统计分析。结果85例(65%)患者首诊时伴随有腰酸背痛腿抽筋等症状,治疗3个月后明显好转,1年后仅少数人遗留轻度的腰酸背疼,与治疗前差异显著;不论是骨密度绝对值还是T值,治疗前后均有显著性差异;132例患者在1年的治疗期间仅有2例发生新发骨折,占所有患者的1.51%。结论正规的抗骨质疏松治疗不仅可以快速显著地改善临床症状,而且可以提高骨密度,并能预防骨折、降低骨折发生率。
目的:通過對132例原髮性骨質疏鬆癥患者抗骨質疏鬆規範治療1年前後的對比,明確骨質疏鬆癥早期診斷治療的意義。方法以我院2011-2012年間門診診治的有完整記錄的原髮性骨質疏鬆癥患者132例為研究對象,給予正規抗骨質疏鬆治療1年,對治療前後每位患者的臨床癥狀[視覺模擬評分( Visual Analogue Score,VAS),雙能X線吸取測量法( Dual Energy X-ray Absorptiometry,DEXA)測定骨密度(Bone mineral density,BMD)]、骨摺髮生率進行對比和統計分析。結果85例(65%)患者首診時伴隨有腰痠揹痛腿抽觔等癥狀,治療3箇月後明顯好轉,1年後僅少數人遺留輕度的腰痠揹疼,與治療前差異顯著;不論是骨密度絕對值還是T值,治療前後均有顯著性差異;132例患者在1年的治療期間僅有2例髮生新髮骨摺,佔所有患者的1.51%。結論正規的抗骨質疏鬆治療不僅可以快速顯著地改善臨床癥狀,而且可以提高骨密度,併能預防骨摺、降低骨摺髮生率。
목적:통과대132례원발성골질소송증환자항골질소송규범치료1년전후적대비,명학골질소송증조기진단치료적의의。방법이아원2011-2012년간문진진치적유완정기록적원발성골질소송증환자132례위연구대상,급여정규항골질소송치료1년,대치료전후매위환자적림상증상[시각모의평분( Visual Analogue Score,VAS),쌍능X선흡취측량법( Dual Energy X-ray Absorptiometry,DEXA)측정골밀도(Bone mineral density,BMD)]、골절발생솔진행대비화통계분석。결과85례(65%)환자수진시반수유요산배통퇴추근등증상,치료3개월후명현호전,1년후부소수인유류경도적요산배동,여치료전차이현저;불론시골밀도절대치환시T치,치료전후균유현저성차이;132례환자재1년적치료기간부유2례발생신발골절,점소유환자적1.51%。결론정규적항골질소송치료불부가이쾌속현저지개선림상증상,이차가이제고골밀도,병능예방골절、강저골절발생솔。
Objective To illuminate the significance of early diagnosis of osteoporosis by comparison of regular anti-osteoporosis therapy for 132 primary osteoporosis patients before and after treatment.Methods Data of 132 osteoporosis patients who received regular anti-osteoporosis therapy for 1 year in the out-patient of our hospital from 2011 to 2012 were collected.Clinical symptom ( Visual Analogue Score, VAS ) , bone mineral density ( Dual Energy X-ray Absorptiometry, DEXA ) , and the incidence of fractures before and after treatment were compared and statistically analyzed.Results Backache and leg cramps occurred in 85 patients (65%) at initial diagnosis, which were relieved greatly after 3-month treatment.Only few patients remained mild back pain after 1-year therapy.Both absolute value of bone mineral density and the T-score changed significantly after the treatment.Only 2 cases of new fracture occurred during the 1-year treatment in 132 patients ( 1.51%) .Conclusion Regular anti-osteoporosis treatment can not only rapidly relieve the clinical symptoms, but also improve bone mineral density, prevent fractures, and reduce the incidence of fractures.