中国神经精神疾病杂志
中國神經精神疾病雜誌
중국신경정신질병잡지
CHINESE JOURNAL OF NERVOUS AND MENTAL DISEASES
2015年
4期
214-218
,共5页
谢孟杰%陈楠%邹义壮%张勇%郑文静%郜肖肖%温玉杰%刘礼丽
謝孟傑%陳楠%鄒義壯%張勇%鄭文靜%郜肖肖%溫玉傑%劉禮麗
사맹걸%진남%추의장%장용%정문정%고초초%온옥걸%류례려
精神分裂症%前瞻性记忆%回顾性记忆%工作记忆%听觉逻辑记忆%视觉再现记忆
精神分裂癥%前瞻性記憶%迴顧性記憶%工作記憶%聽覺邏輯記憶%視覺再現記憶
정신분렬증%전첨성기억%회고성기억%공작기억%은각라집기억%시각재현기억
Schizophrenia%prospective memory(PM)%Retrospective memory(RM)%Working memory(WM)%Auditory logical memory(ALM)%Visual reproduction memory(VRM)
目的:分析慢性精神分裂症患者前瞻性记忆(prospective memory,PM)与回顾性记忆(retrospective memory,RM)损害状况,探讨慢性精神分裂症患者PM与RM的关联。方法纳入50例慢性精神分裂症患者和50名正常对照,用中文版剑桥前瞻性记忆测试量表(Cambridge prospective memory test,C-CAMPROMPT)评估基于事件的前瞻性记忆(event-based PM,EBPM)和基于时间的前瞻性记忆(time-based PM,TBPM),数字序列(digital span,DS)测验评估工作记忆(working memory,WM),逻辑记忆(logical memory)测验和视觉再现(visual reproduction,VR)测验分别评估即刻听觉逻辑记忆(immediate auditory logical memory,IALM)、延迟性听觉逻辑记忆(delayed auditory logical memory,DALM)和即刻视觉再现记忆(immediate visual reproduction memory, IVRM)、延迟性视觉再现记忆(delayed visual reproduction memory,DVRM),并根据标准分数将患者各量表得分转换为可进行量表间比较的损伤指数。结果患者组的EBPM[(7.9±3.4)vs.(13.7±2.9)]、TBPM[(6.9±3.6)vs.(13.0±3.2)]、DS-顺背[(5.8±2.0)vs.(7.5±2.2)]、DS-倒背[(6.5±1.9)vs.(8.2±2.8)]、IALM[(8.3±3.1)vs.(11.9±2.5)]、DALM[(7.4±3.7)vs.(11.8±2.6)]、IVRM[(8.0±2.7)vs.(11.2±3.8)]及DVRM[(7.7±3.5)vs.(10.8±2.7)]得分均低于对照组,差异有统计学意义(均P<0.05);患者组EBPM损伤指数和TBPM损伤指数均大于DS-顺背损伤指数、DS-倒背损伤指数、IALM损伤指数、IVRM损伤指数、DVRM损伤指数(均P<0.05),与DALM损伤指数差异均无统计学意义(P>0.05)。患者组PM总分与除IVRM(P=0.155)外RM各测验得分的相关关系均有统计学意义(均P<0.05)。结论慢性精神分裂症患者存在前瞻性记忆和回顾性记忆损害,前瞻性记忆损害较回顾性记忆损害严重,且两种损害相互关联。
目的:分析慢性精神分裂癥患者前瞻性記憶(prospective memory,PM)與迴顧性記憶(retrospective memory,RM)損害狀況,探討慢性精神分裂癥患者PM與RM的關聯。方法納入50例慢性精神分裂癥患者和50名正常對照,用中文版劍橋前瞻性記憶測試量錶(Cambridge prospective memory test,C-CAMPROMPT)評估基于事件的前瞻性記憶(event-based PM,EBPM)和基于時間的前瞻性記憶(time-based PM,TBPM),數字序列(digital span,DS)測驗評估工作記憶(working memory,WM),邏輯記憶(logical memory)測驗和視覺再現(visual reproduction,VR)測驗分彆評估即刻聽覺邏輯記憶(immediate auditory logical memory,IALM)、延遲性聽覺邏輯記憶(delayed auditory logical memory,DALM)和即刻視覺再現記憶(immediate visual reproduction memory, IVRM)、延遲性視覺再現記憶(delayed visual reproduction memory,DVRM),併根據標準分數將患者各量錶得分轉換為可進行量錶間比較的損傷指數。結果患者組的EBPM[(7.9±3.4)vs.(13.7±2.9)]、TBPM[(6.9±3.6)vs.(13.0±3.2)]、DS-順揹[(5.8±2.0)vs.(7.5±2.2)]、DS-倒揹[(6.5±1.9)vs.(8.2±2.8)]、IALM[(8.3±3.1)vs.(11.9±2.5)]、DALM[(7.4±3.7)vs.(11.8±2.6)]、IVRM[(8.0±2.7)vs.(11.2±3.8)]及DVRM[(7.7±3.5)vs.(10.8±2.7)]得分均低于對照組,差異有統計學意義(均P<0.05);患者組EBPM損傷指數和TBPM損傷指數均大于DS-順揹損傷指數、DS-倒揹損傷指數、IALM損傷指數、IVRM損傷指數、DVRM損傷指數(均P<0.05),與DALM損傷指數差異均無統計學意義(P>0.05)。患者組PM總分與除IVRM(P=0.155)外RM各測驗得分的相關關繫均有統計學意義(均P<0.05)。結論慢性精神分裂癥患者存在前瞻性記憶和迴顧性記憶損害,前瞻性記憶損害較迴顧性記憶損害嚴重,且兩種損害相互關聯。
목적:분석만성정신분렬증환자전첨성기억(prospective memory,PM)여회고성기억(retrospective memory,RM)손해상황,탐토만성정신분렬증환자PM여RM적관련。방법납입50례만성정신분렬증환자화50명정상대조,용중문판검교전첨성기억측시량표(Cambridge prospective memory test,C-CAMPROMPT)평고기우사건적전첨성기억(event-based PM,EBPM)화기우시간적전첨성기억(time-based PM,TBPM),수자서렬(digital span,DS)측험평고공작기억(working memory,WM),라집기억(logical memory)측험화시각재현(visual reproduction,VR)측험분별평고즉각은각라집기억(immediate auditory logical memory,IALM)、연지성은각라집기억(delayed auditory logical memory,DALM)화즉각시각재현기억(immediate visual reproduction memory, IVRM)、연지성시각재현기억(delayed visual reproduction memory,DVRM),병근거표준분수장환자각량표득분전환위가진행량표간비교적손상지수。결과환자조적EBPM[(7.9±3.4)vs.(13.7±2.9)]、TBPM[(6.9±3.6)vs.(13.0±3.2)]、DS-순배[(5.8±2.0)vs.(7.5±2.2)]、DS-도배[(6.5±1.9)vs.(8.2±2.8)]、IALM[(8.3±3.1)vs.(11.9±2.5)]、DALM[(7.4±3.7)vs.(11.8±2.6)]、IVRM[(8.0±2.7)vs.(11.2±3.8)]급DVRM[(7.7±3.5)vs.(10.8±2.7)]득분균저우대조조,차이유통계학의의(균P<0.05);환자조EBPM손상지수화TBPM손상지수균대우DS-순배손상지수、DS-도배손상지수、IALM손상지수、IVRM손상지수、DVRM손상지수(균P<0.05),여DALM손상지수차이균무통계학의의(P>0.05)。환자조PM총분여제IVRM(P=0.155)외RM각측험득분적상관관계균유통계학의의(균P<0.05)。결론만성정신분렬증환자존재전첨성기억화회고성기억손해,전첨성기억손해교회고성기억손해엄중,차량충손해상호관련。
Objectives To compare prospective memory (PM) deficits with retrospective memory (RM) deficits and to explore the correlation between PM and RM in chronic schizophrenia. Methods Fifty chronic schizophrenia pa?tients and fifty healthy controls were recruited. The PM performance [event-based PM (EBPM) and time-based PM (TB?PM)] were evaluated by the Chinese version of the Cambridge Prospective Memory Test (C-CAMPROMPT); working memory (WM) was evaluated by the digital span subtest (DS);immediate auditory logical memory (IALM), delayed audito?ry logical memory (DALM), immediate visual reproduction memory (IVRM) and delayed visual reproduction memory (DVRM) were evaluated by the logical memory and visual reproduction subtest. The score of each test was transformed to comparable standard score. Results Patients performed significantly worse on EBPM [(7.9 ± 3.4) vs. (13.7 ± 2.9)], TBPM [(6.9±3.6) vs. (13.0±3.2)], DS [sequence:(5.8±2.0) vs. (7.5±2.2);backward:(6.5±1.9) vs. (8.2±2.8)], IALM [(8.3±3.1) vs. (11.9 ± 2.5)], DALM [(7.4 ± 3.7) vs. (11.8 ± 2.6)], IVRM [(8.0 ± 2.7) vs. (11.2 ± 3.8)], and DVRM [(7.7 ± 3.5) vs. (10.8 ± 2.7)] scores than controls (P<0.05). The extent of deficits of EBPM and TBPM were greater than those of DS (sequence and backward), IALM, DALM, IVRM and DVRM (P<0.05), but not DALM (P>0.05). The performance of PM in chronic schizophrenia was significantly related to DS (sequence and backward), IALM, DALM and DVRM (P<0.05), but not IVRM (P=0.155). Conclusion:There are greater prospective memory deficits than retrospective memory deficits in chron?ic schizophrenia and the prospective memory deficits are correlated with the retrospective memory deficits in chronic schizophrenia.