CAJ | 학술논문

目的：采用相位对比法（PC）磁共振成像（MRI）测量健康志愿者的主、肺动脉起始部净血流量，并进行比较，以验证 PC MRI 测量主、肺动脉起始部净血流量的准确性及可重复性。方法选取2012年1月—2013年12月昆明医科大学第二附属医院进行体检的健康志愿者31例，采用 PC MRI 测量心动周期内主、肺动脉起始部净血流量，观察 PC MRI 测量主、肺动脉起始部净血流量的准确性；前后两次测量9例健康志愿者主、肺动脉起始部净血流量，观察 PC MRI 测量主、肺动脉起始部净血流量的可重复性。结果主、肺动脉起始部时间-净血流量图呈逐渐上升曲线，相对应心脏的收缩期，主、肺动脉起始部净血流量曲线表现为倾斜度较大、光滑且连续的曲线；相对应心脏的舒张期，主、肺动脉起始部净血流量曲线表现为逐渐向上、波形较平缓、光滑且连续的曲线。主动脉起始部净血流量（72.8±12.2）ml，肺动脉起始部净血流量（73.8±13.8）ml，差异无统计学意义（t =-1.924，P =0.64）。主动脉起始部净血流量与肺动脉起始部净血流量呈正相关（r =0.94，P <0.05），方程为：Y =-3.825＋1.066X。第1次与第2次测量主、肺动脉起始部净血流量比较，差异均无统计学意义（P >0.05）。第1次与第2次测量主动脉起始部净血流量呈正相关（r =0.91，P <0.05），方程为：Y =-6.669＋1.078X。第1次与第2次测量肺动脉起始部净血流量呈正相关（r =0.92，P =0.001），方程为：Y =5.391＋0.923X。结论 PC MRI 是一种无创、安全、准确、信息量大的检查方法，且不受肺气、骨骼的影响，是研究主、肺动脉起始部净血流量的好方法。
목적：채용상위대비법（PC）자공진성상（MRI）측량건강지원자적주、폐동맥기시부정혈류량，병진행비교，이험증 PC MRI 측량주、폐동맥기시부정혈류량적준학성급가중복성。방법선취2012년1월—2013년12월곤명의과대학제이부속의원진행체검적건강지원자31례，채용 PC MRI 측량심동주기내주、폐동맥기시부정혈류량，관찰 PC MRI 측량주、폐동맥기시부정혈류량적준학성；전후량차측량9례건강지원자주、폐동맥기시부정혈류량，관찰 PC MRI 측량주、폐동맥기시부정혈류량적가중복성。결과주、폐동맥기시부시간-정혈류량도정축점상승곡선，상대응심장적수축기，주、폐동맥기시부정혈류량곡선표현위경사도교대、광활차련속적곡선；상대응심장적서장기，주、폐동맥기시부정혈류량곡선표현위축점향상、파형교평완、광활차련속적곡선。주동맥기시부정혈류량（72.8±12.2）ml，폐동맥기시부정혈류량（73.8±13.8）ml，차이무통계학의의（t =-1.924，P =0.64）。주동맥기시부정혈류량여폐동맥기시부정혈류량정정상관（r =0.94，P <0.05），방정위：Y =-3.825＋1.066X。제1차여제2차측량주、폐동맥기시부정혈류량비교，차이균무통계학의의（P >0.05）。제1차여제2차측량주동맥기시부정혈류량정정상관（r =0.91，P <0.05），방정위：Y =-6.669＋1.078X。제1차여제2차측량폐동맥기시부정혈류량정정상관（r =0.92，P =0.001），방정위：Y =5.391＋0.923X。결론 PC MRI 시일충무창、안전、준학、신식량대적검사방법，차불수폐기、골격적영향，시연구주、폐동맥기시부정혈류량적호방법。
Objectjve In order to evaluate the accuracy and repeatability of PC MRI in measuring the net blood flow volume of aorta and main pulmonary artery,the net blood flow volume of aorta and main pulmonary artery is measured by using PC MRI among healthy volunteers,the results were compared. Methods 31 healthy volunteers who received health examination in the Second Affiliated Hospital of Kunming Medical University from January 2012 to December 2013,were selected as study subjects,the net blood flow volume of the initial part of aorta and pulmonary artery in the cardiac circle was measured by using PC MRI,the accuracy of PC MRI in measuring the net blood flow volume was analyzed. To find out the measurement repeatability of net blood flow volume of aorta and main pulmonary artery by using PC MR,the net blood flow volume of aorta and pulmonary artery is measured by using PC MRI among 9 healthy volunteers twice. Results The time - net blood flow volume diagram for the initial part of aorta and pulmonary artery showed a rising curve. In systole,the time - net blood flow volume diagram for the initial part of aorta and pulmonary artery showed a smooth,continuous curve with high inclination;in diastole,the time - blood flow volume diagram for the initial part of aorta and pulmonary artery showed a smooth,continuous and rising curve with mild waveform. There was no significant difference in the net blood flow volume between the initial part of aorta artery〔(72. 8 ± 12. 2) ml〕and the initial part of pulmonary artery〔(73. 8 ± 13. 8)ml〕(t = - 1. 924,P = 0. 64). The net blood flow volume of aorta was positively correlated with the net blood flow volume of main pulmonary artery( r = 0. 94,P < 0. 05),the equation:Y= - 3. 825 + 1. 066X. There was no significant difference in the net blood flow volume of aorta and main pulmonary artery between the first time and the second time(P > 0. 05). The net blood flow volume of aorta for the first time was positively correlated with the net blood flow volume of aorta for the second time(r = 0. 91,P < 0. 05),the equation:Y = - 6. 669 + 1. 078X. The net blood flow volume of main pulmonary artery for the first time was positively correlated with the net blood flow volume of main pulmonary artery for the second time(r = 0. 92,P = 0. 001),the equation:Y = 5. 391 + 0. 923X. Conclusjon PC MRI is a noninvasive,safe,accurate and informative method, and is not affected by air and bone, so it is a good method for hemodynamic study of aorta and pulmonary artery.