中国骨质疏松杂志
中國骨質疏鬆雜誌
중국골질소송잡지
CHINESE JOURNAL OF OSTEOPOROSIS
2015年
4期
472-475
,共4页
张勤%王永美%冯柳娴%曹敏
張勤%王永美%馮柳嫻%曹敏
장근%왕영미%풍류한%조민
股骨颈上部区域%骨密度%骨质疏松症%正常人群
股骨頸上部區域%骨密度%骨質疏鬆癥%正常人群
고골경상부구역%골밀도%골질소송증%정상인군
Upper part of the femoral neck%Bone mineral density%Osteoporosis%Normal people
目的：通过测量广州地区正常汉族人群的股骨颈上部区域骨密度（ bone mineral density， BMD），确定本地区股骨颈上部区域骨密度的正常参考值，并探讨其随年龄变化的规律。方法使用美国Lunar公司生产的DPX型双能X线骨密度仪（ dual－energy x－ray absorptiometer，DXA）对广州地区20岁以上汉族健康人1342例（男648人，女694人）双侧股骨近端BMD进行测定。按不同性别29岁及以下、70岁及以上各为一个年龄组，30～69岁每5岁分为一年龄组，得出骨密度均值、标准差及累计丢失百分率。结果①广州地区男、女性双侧股骨上部1／2区域骨密度峰值（ peak bone density，PBD）均出现在20～29岁年龄组；此后，随年龄增长BMD降低，女性BMD在45岁后加速下降，男性无加速下降倾向。②广州地区双侧股骨颈中段上部1／2区域骨质疏松症的诊断参考值：男性为0．627 g／cm2，女性为0．487 g／cm2。结论股骨上部1／2区域是检测骨质疏松的敏感部位，其BMD测量值具有良好的年龄相关性，且女性骨质丢失增速出现年龄更早。
目的：通過測量廣州地區正常漢族人群的股骨頸上部區域骨密度（ bone mineral density， BMD），確定本地區股骨頸上部區域骨密度的正常參攷值，併探討其隨年齡變化的規律。方法使用美國Lunar公司生產的DPX型雙能X線骨密度儀（ dual－energy x－ray absorptiometer，DXA）對廣州地區20歲以上漢族健康人1342例（男648人，女694人）雙側股骨近耑BMD進行測定。按不同性彆29歲及以下、70歲及以上各為一箇年齡組，30～69歲每5歲分為一年齡組，得齣骨密度均值、標準差及纍計丟失百分率。結果①廣州地區男、女性雙側股骨上部1／2區域骨密度峰值（ peak bone density，PBD）均齣現在20～29歲年齡組；此後，隨年齡增長BMD降低，女性BMD在45歲後加速下降，男性無加速下降傾嚮。②廣州地區雙側股骨頸中段上部1／2區域骨質疏鬆癥的診斷參攷值：男性為0．627 g／cm2，女性為0．487 g／cm2。結論股骨上部1／2區域是檢測骨質疏鬆的敏感部位，其BMD測量值具有良好的年齡相關性，且女性骨質丟失增速齣現年齡更早。
목적：통과측량엄주지구정상한족인군적고골경상부구역골밀도（ bone mineral density， BMD），학정본지구고골경상부구역골밀도적정상삼고치，병탐토기수년령변화적규률。방법사용미국Lunar공사생산적DPX형쌍능X선골밀도의（ dual－energy x－ray absorptiometer，DXA）대엄주지구20세이상한족건강인1342례（남648인，녀694인）쌍측고골근단BMD진행측정。안불동성별29세급이하、70세급이상각위일개년령조，30～69세매5세분위일년령조，득출골밀도균치、표준차급루계주실백분솔。결과①엄주지구남、녀성쌍측고골상부1／2구역골밀도봉치（ peak bone density，PBD）균출현재20～29세년령조；차후，수년령증장BMD강저，녀성BMD재45세후가속하강，남성무가속하강경향。②엄주지구쌍측고골경중단상부1／2구역골질소송증적진단삼고치：남성위0．627 g／cm2，녀성위0．487 g／cm2。결론고골상부1／2구역시검측골질소송적민감부위，기BMD측량치구유량호적년령상관성，차녀성골질주실증속출현년령경조。
Objective By measuring bone mineral density ( BMD ) at the upper part of the femoral neck among the Han nationality in Guangzhou area, to determine the reference value of BMD in normal people in this area, and to investigate the BMD change according to age.Methods BMD of proximal femurs was measured using DEXA ( Lunar, US) in 1342 healthy people of the Han nationality who were more than 20 years old (648 males and 694 females).Patients were divided into groups according gender and age.Those who were below 29 or over 70 were in separate groups.Those who were between 30 and 69 years-old were in groups with a 5-year interval.The mean and standard deviation of BMD and accumulate bone lose were calculated.Results 1) The peak bone density (PBD) of the upper part of the femoral neck was in the group whose age was between 20 and 29 years old in both males and females.Afterwards, BMD decreased with the increasing of age.BMD decreased rapidly in the female whose age was more than 45, but the tendency of rapid decrease in BMD was not in males at the same age.2) The reference values of BMD for osteoporosis diagnosis at the upper part of the femoral neck were 0.627g/cm2 in males and 0.487 g/cm2 in females in the Han nationality in Guangzhou area.Conclusion Measuring BMD at the upper part of the femoral neck is a sensitive method to diagnose osteoporosis.The measured value has better correlation with age.The appearance of bone loss occurs earlier in females.
