CAJ | 학술논문

目的：探讨中央区淋巴结清扫术在甲状腺乳头状癌中的应用价值。方法回顾性分析我院192例初次诊治且术前无任何局部并发症的甲状腺乳头状癌患者临床病理资料。结果本组患者总体颈部淋巴结转移率为52.1%，中央区淋巴结转移率为50.0%。微小癌组与非微小癌组颈部淋巴结转移率分别为44.1%、66.7%，中央区淋巴结转移率分别为43.3%、63.1%。微小癌组与非微小癌组淋巴结转移发生率有明显差异（χ2＝9.593，P＜0.05）。微小癌组中，原发灶大小对淋巴结转移率无明显影响（χ2＝0.982，P＞0.05），多发灶患者较单发灶者更容易出现颈淋巴结转移（χ2＝4.334， P＜0.05）。结论非微小甲状腺乳头状癌应常规进行中央区淋巴结清扫术，微小甲状腺癌也应建议中央区淋巴结清扫术。
목적：탐토중앙구림파결청소술재갑상선유두상암중적응용개치。방법회고성분석아원192례초차진치차술전무임하국부병발증적갑상선유두상암환자림상병리자료。결과본조환자총체경부림파결전이솔위52.1%，중앙구림파결전이솔위50.0%。미소암조여비미소암조경부림파결전이솔분별위44.1%、66.7%，중앙구림파결전이솔분별위43.3%、63.1%。미소암조여비미소암조림파결전이발생솔유명현차이（χ2＝9.593，P＜0.05）。미소암조중，원발조대소대림파결전이솔무명현영향（χ2＝0.982，P＞0.05），다발조환자교단발조자경용역출현경림파결전이（χ2＝4.334， P＜0.05）。결론비미소갑상선유두상암응상규진행중앙구림파결청소술，미소갑상선암야응건의중앙구림파결청소술。
Objective To discuss the application value of central group neck lymph node dissection in the patients with papillary thyroid carcinoma (PTC). Methods 192 cases with PTC were retrospectively reviewed. All the patients without any complications preoperative were first diagnosed and treated in our hospital. Results The rate of cervical lymphatic metastasis was 52.1% overall, while the rate of central group lymph node metastasis was 50.0%. The rate of cervical lymphatic metastasis in the group of papillary thyroid microcarcinoma (PTMC) and the group of Non-PTMC were 44.1%and 66.7%respectively, while the rate of central group lymph node metastasis were 43.3% and 63.1% respectively. There was significance of cervical lymph node metastasis between the group of PTMC and the group of Non-PTMC. The tumor size had no effect on lymphatic metastasis in the group of PTMC. There was significance of cervical lymph node metastasis between solitary PTMC group and multifocal PTMC group. Conclusion The central neck dissection should be performed routinely for Non-PTMC patients, and should also be advised for PTMC patients.