CAJ | 학술논문

目的：探讨龙血竭胶囊联合替硝唑治疗慢性宫颈炎的疗效分析及对患者免疫球蛋白水平的影响。方法选取2013年1月～2014年6月间舟山市普陀区妇幼保健与计划生育服务中心收治的90例符合入选标准的慢性宫颈炎患者，使用分层随机法分为对照组（n＝45）和观察组（n＝45）。常规治疗基础上，对照组给予替硝唑治疗，观察组在对照组的基础上联合应用龙血竭胶囊治疗。观察比较2组患者临床疗效、症状积分及免疫球蛋白水平等情况。结果观察组的治疗总有效率为95.6％，显著高于对照组80.0％的总有效率（P＜0.05）。治疗后，与对照组相比，观察组分泌物、宫颈病变程度症状积分明显降低，免疫功能指标IgG、IgM和IgA明显升高，均有统计学意义（P＜0.05）。对照组和观察组分别出现2例和3例下腹疼痛，未经治疗自行缓解。结论龙血竭胶囊联合替硝唑治疗慢性宫颈炎的疗效可靠，可以显著改善症状，提高机体免疫球蛋白水平。
목적：탐토룡혈갈효낭연합체초서치료만성궁경염적료효분석급대환자면역구단백수평적영향。방법선취2013년1월～2014년6월간주산시보타구부유보건여계화생육복무중심수치적90례부합입선표준적만성궁경염환자，사용분층수궤법분위대조조（n＝45）화관찰조（n＝45）。상규치료기출상，대조조급여체초서치료，관찰조재대조조적기출상연합응용룡혈갈효낭치료。관찰비교2조환자림상료효、증상적분급면역구단백수평등정황。결과관찰조적치료총유효솔위95.6％，현저고우대조조80.0％적총유효솔（P＜0.05）。치료후，여대조조상비，관찰조분비물、궁경병변정도증상적분명현강저，면역공능지표IgG、IgM화IgA명현승고，균유통계학의의（P＜0.05）。대조조화관찰조분별출현2례화3례하복동통，미경치료자행완해。결론룡혈갈효낭연합체초서치료만성궁경염적료효가고，가이현저개선증상，제고궤체면역구단백수평。
Objective To investigate the clinical effect of longxuejie capsule in combination with tinidazole in the treatment of chronic cervicitis and its effects on levels of immunoglobulin.Methods 90 cases in our hospital from January 2013 to June 2014, with chronic cervicitis meeting the inclusion critera were randomly divided into 2 groups by method of stratified randomization equally.Control group (n=45) was treated with tinidazole and conventional treatments, while observation group ( n =45 ) was treated with tinidazole and longxuejie capsule.Then, the curative efficacy, scale of symptoms and levels of immunoglobulin were observed and compared.Results The therapeutic efficiency ratio of observation group was 95.6%, which was significantly higher than that of control group ( 80.0%, P<0.05 ).After the treatment, in comparison with the control group, scale of cervical secretion and severity of cervical lesion was statistically lower respectively than observation group ( P<0.05 ).As to immunological function, concentrations of IgG, IgM, IgA in observation group were statistically higher than that in control group after the treatment (P<0.05).The control group and observation group respectively in 2 cases and 3 cases of abdominal pain, alleviated by themselves without treatment.Conclusion longxuejie capsule combined with tinidazole is effective and reliable for patients with chronic cervicitis, which significantly improves symptoms and elevates levels of immunoglobulin.