CAJ | 학술논문

目的：总结基底动脉尖综合征（ TOBS）的临床表现、治疗及预后。方法回顾性分析2009年6月—2014年3月在福建医科大学附属闽东医院住院治疗的15例TOBS患者的临床资料，总结其临床表现、治疗及预后。结果 TOBS患者以中老年男性多见，临床主要表现为不同程度的意识障碍、眼球运动障碍、瞳孔改变，CT或MRI可以发现基底动脉顶端血管供血区双侧两处以上梗死灶，以丘脑、中脑多见。患者均行机械取栓、溶栓、抗凝等治疗，预后较好。结论 TOBS临床表现形式多样，病死率较高，早期诊断和及时治疗可明显改善患者预后。
목적：총결기저동맥첨종합정（ TOBS）적림상표현、치료급예후。방법회고성분석2009년6월—2014년3월재복건의과대학부속민동의원주원치료적15례TOBS환자적림상자료，총결기림상표현、치료급예후。결과 TOBS환자이중노년남성다견，림상주요표현위불동정도적의식장애、안구운동장애、동공개변，CT혹MRI가이발현기저동맥정단혈관공혈구쌍측량처이상경사조，이구뇌、중뇌다견。환자균행궤계취전、용전、항응등치료，예후교호。결론 TOBS림상표현형식다양，병사솔교고，조기진단화급시치료가명현개선환자예후。
Objective To summarize the clinical features, treatment and prognosis of top of the basilar artery syndrome( TOBS). Methods A total of 15 patients with TOBS were selected in Mindong Hospital Affiliated to Fujian Medical University from June 2009 to March 2014,and their clinical data was retrospectively analyzed,the clinical features,treatment and prognosis of TOBS summarized. Results Middle-aged and aged male was main crowd,the main clinical features included varying degrees of conscious disturbance,eyeball movement disorder and pupil changes. CT or MRI showed over 2 infarct lesions of both sides of top of the basilar artery,commonly in thalamus and midbrain. All of the patients were treated with mechanical thrombus extraction,thrombolysis and anticoagulation therapy,and the prognosis was good. Conclusion The clinical features of TOBS was various, and the case fatality rate was high, early diagnosis and timely treatment can effectively improve the prognosis.