CAJ | 학술논문

通过水热合成和常温合成的方法制备了介孔 Fe3O4@mSiO2@Cu2+磁性复合纳米粒子（NPs），其具有均匀的尺寸大小、良好的磁性能和特异的选择性。本研究将合成的 NPs 用作磁性固相萃取（ MSPE）介质，结合高效液相色谱（ HPLC）发展了一种测定水样品中痕量微囊藻毒素 MC-LR的方法。在优化 MSPE和 HPLC条件后，该方法在0.1~15μg／L范围内呈现良好的线性，线性相关系数（ r）为0.9994，检出限为0.025μg／L，定量限为0.082μg／L。进一步将该方法用于水样中痕量藻毒素分析，结果发现回收率达到78％。这一结果表明：制得的磁性纳米粒子具有良好的萃取性能，可有效用于水样中痕量藻毒素的测定。
통과수열합성화상온합성적방법제비료개공 Fe3O4@mSiO2@Cu2+자성복합납미입자（NPs），기구유균균적척촌대소、량호적자성능화특이적선택성。본연구장합성적 NPs 용작자성고상췌취（ MSPE）개질，결합고효액상색보（ HPLC）발전료일충측정수양품중흔량미낭조독소 MC-LR적방법。재우화 MSPE화 HPLC조건후，해방법재0.1~15μg／L범위내정현량호적선성，선성상관계수（ r）위0.9994，검출한위0.025μg／L，정량한위0.082μg／L。진일보장해방법용우수양중흔량조독소분석，결과발현회수솔체도78％。저일결과표명：제득적자성납미입자구유량호적췌취성능，가유효용우수양중흔량조독소적측정。
Mesoporous magnetic nanoparticles of Fe3O4@mSiO2@Cu2+ were synthesized by two methods of hydrothermal synthesis and room temperature synthesis. The synthesized meso-porous Fe3O4@mSiO2@Cu2+ nanoparticles presented uniform sizes,good magnetic properties and specific selectivity. In this work,a novel magnetic solid-phase extraction( MSPE)method based on mesoporous Fe3O4@mSiO2@Cu2+ nanoparticles( NPs)coupled with high perform-ance liquid chromatography( HPLC ) was developed for the simultaneous extraction of trace amount of microcystin-LR( MC-LR ) in water samples. The MSPE extraction conditions and HPLC conditions were optimized. The results showed that good linear relationship( r=0. 999 4) was obtained between peak area and mass concentration of MC-LR in the range of 0. 1-15μg/L. The limit of detection was 0. 025 μg/L,and the limit of quantification was 0. 082 μg/L. Furthermore,this method was used for the analysis of algal toxins in water samples with the recovery of 78%. The results indicated that Fe3O4@mSiO2@Cu2+ magnetic nanoparticles were good pretreatment alternatives for the concentration of microcystin-LR in water samples.