CAJ | 학술논문

目的：研究并验证帕罗西汀治疗卒中后抑郁及神经功能缺失的临床治疗效果。方法选取该院收治的110例脑卒中后抑郁患者，将其随机划分为研究组和对照组，对照组利用常规的治疗方法来实施，研究组则不仅采用对照组的常规治疗方案，同时使用大约为20~40 mg/d的帕罗西汀进行辅助，治疗6周；采用HAMA得分来对患者的神经功能缺损的治疗改善效果进行合理的研究评估。结果研究组治疗抑郁的有效率达到82%，治疗神经功能损伤的有效率则为91%；对照组治疗抑郁的有效率是45%，神经功能损伤治疗有效率则为65%，两组之间差异有统计学意义(P<0.05)。结论帕罗西汀针对脑卒中后抑郁症状的治疗具有明显的缓解作用，临床应用价值显著。
목적：연구병험증파라서정치료졸중후억욱급신경공능결실적림상치료효과。방법선취해원수치적110례뇌졸중후억욱환자，장기수궤화분위연구조화대조조，대조조이용상규적치료방법래실시，연구조칙불부채용대조조적상규치료방안，동시사용대약위20~40 mg/d적파라서정진행보조，치료6주；채용HAMA득분래대환자적신경공능결손적치료개선효과진행합리적연구평고。결과연구조치료억욱적유효솔체도82%，치료신경공능손상적유효솔칙위91%；대조조치료억욱적유효솔시45%，신경공능손상치료유효솔칙위65%，량조지간차이유통계학의의(P<0.05)。결론파라서정침대뇌졸중후억욱증상적치료구유명현적완해작용，림상응용개치현저。
Objective to study and validation of paroxetine in the treatment of poststroke depression and nerve function lack effective treatment.Methods After selecting our hospital 110 cases of stroke in patients with depression were randomly divided into the study group and the control group, the control group using conventional treatment methods to implement the study group not only with conventional therapy in the control group, while using about paroxetine 20~40mg / d of adjuvant treatment six weeks; HAMA score to make reasonable use of research to improve the assessment of treatment effects in patients with neurological defects.Results Study group to treat depression efficiency reached 82%, with the treatment of neurological damage, compared with 91% efficiency; control group, treatment of depression is 45% efficient, effective treatment of neurological damage, compared with 65% between the two groups have significant differences (P<0.05), with statistical significance.Conclusion Paroxetine for the treatment of depressive symptoms after stroke obvious relief, the clinical value of significant.