中外医疗
中外醫療
중외의료
CHINA FOREIGN MEDICAL TREATMENT
2015年
9期
119-120
,共2页
尿激酶%小剂量%急性心肌梗死%溶栓治疗
尿激酶%小劑量%急性心肌梗死%溶栓治療
뇨격매%소제량%급성심기경사%용전치료
Urokinase%Small dose%Acute myocardial infarction%Thrombolytic therapy
目的：小剂量尿激酶在心肌梗死溶栓治疗中的疗效分析。方法选取2012年7月—2014年4月该院收治的急性心肌梗塞患者75例,并分为常规组(n=38)和小剂量组(n=37)。常规组给予150U尿激酶治疗,小剂量组给予50U尿激酶治疗,比较两组的溶栓再通率、急性期死亡率和溶栓不良反应。结果常规组溶栓总再通率为84.21%,显著高于小剂量组45.94%(c2=12.119,P=0.000)；常规治疗组的急性期死亡率为2.63%,显著低于小剂量组33.33%(c2=4.730,P=0.030)。常规剂量组,溶栓治疗后不良发生率为18.42%,小剂量组则为18.91%,两组比较,差异无统计学意义(c2=0.003,P=0.956)。结论在急性心肌梗塞溶栓治疗中,需给予足量的尿激酶,小剂量的治疗效果不甚理想。
目的：小劑量尿激酶在心肌梗死溶栓治療中的療效分析。方法選取2012年7月—2014年4月該院收治的急性心肌梗塞患者75例,併分為常規組(n=38)和小劑量組(n=37)。常規組給予150U尿激酶治療,小劑量組給予50U尿激酶治療,比較兩組的溶栓再通率、急性期死亡率和溶栓不良反應。結果常規組溶栓總再通率為84.21%,顯著高于小劑量組45.94%(c2=12.119,P=0.000)；常規治療組的急性期死亡率為2.63%,顯著低于小劑量組33.33%(c2=4.730,P=0.030)。常規劑量組,溶栓治療後不良髮生率為18.42%,小劑量組則為18.91%,兩組比較,差異無統計學意義(c2=0.003,P=0.956)。結論在急性心肌梗塞溶栓治療中,需給予足量的尿激酶,小劑量的治療效果不甚理想。
목적：소제량뇨격매재심기경사용전치료중적료효분석。방법선취2012년7월—2014년4월해원수치적급성심기경새환자75례,병분위상규조(n=38)화소제량조(n=37)。상규조급여150U뇨격매치료,소제량조급여50U뇨격매치료,비교량조적용전재통솔、급성기사망솔화용전불량반응。결과상규조용전총재통솔위84.21%,현저고우소제량조45.94%(c2=12.119,P=0.000)；상규치료조적급성기사망솔위2.63%,현저저우소제량조33.33%(c2=4.730,P=0.030)。상규제량조,용전치료후불량발생솔위18.42%,소제량조칙위18.91%,량조비교,차이무통계학의의(c2=0.003,P=0.956)。결론재급성심기경새용전치료중,수급여족량적뇨격매,소제량적치료효과불심이상。
Objective To investigate effect of small dose urokinase in treatment of thrombolytic therapy of acute myocardial infarction.Methods 75 patients from 2012 July to 2014 April in our hospital were selected,and were divided into two groups.The routine group was given 150U urokinase,while small dose group was given 50U urokinase.Thrombolytic recanalization rate, acute mortality and adverse reaction rate of two groups were compared.Results Thrombolysis total recanalization rate of routine group was 84.21%,which was significantly higher than the small dose group(45.94%)(c2=12.119,P=0.000). Thrombolysis total recanalization rate of routine group was 2.63%,which was significantly lower than that of the small dose group(18.91%) (c2=4.730,P=0.030). The adverse reaction rate of routine group was 18.42%,while routine group was 18.91%,and there was no significant difference between two groups(c2=0.003,P=0.956).Conclusion In the thrombolytic therapy of acute myocardial infarction treatment, enough small dose urokinase should be given, and treatment effect of small dose of urokinase is not very ideal.
