中外医疗
中外醫療
중외의료
CHINA FOREIGN MEDICAL TREATMENT
2015年
8期
141-142
,共2页
血凝酶%局部应用%肺癌根治术
血凝酶%跼部應用%肺癌根治術
혈응매%국부응용%폐암근치술
Reptilase%Topical application%Radical resection of lung cancer
目的：探讨分析血凝酶在肺癌根治术中局部应用的止血效果。方法选取该院自2011年5月—2014年2月间，同一主刀医师所作肺癌根治手术92例，皆为肺叶切除加淋巴结清扫，随机分为两组，一组为对照组，（46例）术中创面未使用凝血酶。凝血酶组（46例）术中取血凝酶4单位加入20 mL生理盐水中，向操作创面喷雾覆盖。术后观察病人的全身反应、生命体征，记录术后第1、2、3天的胸引量、胸水红细胞计数等。结果两组病人无明显全身反应，生命体征皆平稳，无差异。凝血酶组与对照组比较，胸引量(324.7±87.9)、(402.6±82.7)mL/d,平均胸水红细胞计数(2.5±0.7)、(5.9±1.2)×105/L。两组比较均有统计学意义(P<0.05)。结论在肺叶切除加淋巴清扫术，关胸前向手术创面喷洒凝血酶，能明显减少术后胸腔引流量、缩短大部分病人术后带管时间。
目的：探討分析血凝酶在肺癌根治術中跼部應用的止血效果。方法選取該院自2011年5月—2014年2月間，同一主刀醫師所作肺癌根治手術92例，皆為肺葉切除加淋巴結清掃，隨機分為兩組，一組為對照組，（46例）術中創麵未使用凝血酶。凝血酶組（46例）術中取血凝酶4單位加入20 mL生理鹽水中，嚮操作創麵噴霧覆蓋。術後觀察病人的全身反應、生命體徵，記錄術後第1、2、3天的胸引量、胸水紅細胞計數等。結果兩組病人無明顯全身反應，生命體徵皆平穩，無差異。凝血酶組與對照組比較，胸引量(324.7±87.9)、(402.6±82.7)mL/d,平均胸水紅細胞計數(2.5±0.7)、(5.9±1.2)×105/L。兩組比較均有統計學意義(P<0.05)。結論在肺葉切除加淋巴清掃術，關胸前嚮手術創麵噴灑凝血酶，能明顯減少術後胸腔引流量、縮短大部分病人術後帶管時間。
목적：탐토분석혈응매재폐암근치술중국부응용적지혈효과。방법선취해원자2011년5월—2014년2월간，동일주도의사소작폐암근치수술92례，개위폐협절제가림파결청소，수궤분위량조，일조위대조조，（46례）술중창면미사용응혈매。응혈매조（46례）술중취혈응매4단위가입20 mL생리염수중，향조작창면분무복개。술후관찰병인적전신반응、생명체정，기록술후제1、2、3천적흉인량、흉수홍세포계수등。결과량조병인무명현전신반응，생명체정개평은，무차이。응혈매조여대조조비교，흉인량(324.7±87.9)、(402.6±82.7)mL/d,평균흉수홍세포계수(2.5±0.7)、(5.9±1.2)×105/L。량조비교균유통계학의의(P<0.05)。결론재폐협절제가림파청소술，관흉전향수술창면분쇄응혈매，능명현감소술후흉강인류량、축단대부분병인술후대관시간。
Objective To observe the reptilase hemostatic effect of local application in radical resection of lung cancer. Methods From may 2011 to February 2014, the author had treated 92 cases of lung cancer patients,they were all treated with lobectomy and lymph node cleaning. The 92 patients undergoing lung cinoma operation were divided into two groups randomly:Group A ( n =46) without received reptilase during and after operation, Group B(n=46) received reptilase 4 units with 20 ml saline solution to spray operation wound. The patient's postoperative systemic reactions and vital signs were observed, at the same time,the volume of pleural effusion and the amount of red blood cells at 1,2 and 3 days after operation were observed. Results There was no signifi-cant difference between Group A and Group B in the patient's postoperative systemic reactions and vital signs. The volume of pleural effusion and amount of red blood cells of group B at 1,2 and 3 days after operation we re less than group A(P<0.05). Con-clusion In lung resection with lymph node cleaning, spraying thrombin closed chest to the surgical wound, It can obviously re-duced the The volume of pleural effusion and amount of red blood cells,shortened the time of drainage tube in body.
