CAJ | 학술논문

目的：探讨糖化血清白蛋白在糖调节受损及新诊断糖尿病人群中的临床意义。方法选取2013年1月—2014年9月于该院门诊进行口服葡萄糖耐量试验者120例分为3组,分别为正常血糖调节组28例,糖调节受损组35例,糖尿病组57例,空腹10h后与早晨行口服葡萄糖耐量试验,取空腹及糖负荷后0.5、2h3个时点取静脉血,测定血糖及空腹糖化血红蛋白、糖化血清白蛋白水平。结果糖化血清白蛋白高于水平分的检出率在糖调节受损组明显高于糖化血红蛋白高于水平分的检出率(P<0.01),其检出率在糖尿病组差异均无统计学意义(P>0.05),糖化血清白蛋白与糖化血红蛋白呈显著正相关(r=0.75,P<0.01),空腹血糖、2h血糖及BMI为糖化血清白蛋白的独立影响因素。结论糖化血清白蛋白测定对于糖尿病诊断、治疗效果和治疗方案的调整更有意义。
목적：탐토당화혈청백단백재당조절수손급신진단당뇨병인군중적림상의의。방법선취2013년1월—2014년9월우해원문진진행구복포도당내량시험자120례분위3조,분별위정상혈당조절조28례,당조절수손조35례,당뇨병조57례,공복10h후여조신행구복포도당내량시험,취공복급당부하후0.5、2h3개시점취정맥혈,측정혈당급공복당화혈홍단백、당화혈청백단백수평。결과당화혈청백단백고우수평분적검출솔재당조절수손조명현고우당화혈홍단백고우수평분적검출솔(P<0.01),기검출솔재당뇨병조차이균무통계학의의(P>0.05),당화혈청백단백여당화혈홍단백정현저정상관(r=0.75,P<0.01),공복혈당、2h혈당급BMI위당화혈청백단백적독립영향인소。결론당화혈청백단백측정대우당뇨병진단、치료효과화치료방안적조정경유의의。
Objective?To?explore?the?clinical?significance?of?glycated?albumin?regulation?damaged?and?newly?diagnosed?diabetes?in?persons?with?sugar.?Methods?In?January?September?to?2013—2014?in?our?hospital?outpatient?oral?glucose?tolerance?test?in?120?cases?of?patients?were?divided?into?three?groups,?respectively?28?cases?of?regulating?normal?blood?glucose?group,?impaired?glucose?regulation?group?35?cases,?57?cases?of?diabetic?group,?after?10?h?fasting?and?morning?for?an?oral?glucose?tolerance?test,?fasting?and?post?glucose?load?in?0.5,?2h?in?three?blood?samples,?determination?of?blood?glucose?and?glycosylated?hemoglobin,?fasting?serum?glycated?albumin?levels;?the?Results?Of?serum?glycated?albumin?level?detection?rate?is?higher?than?the?detection?rate?of?impaired?regulation?in?sugar?group?was?significantly?higher?than?that?of?glycated?hemoglobin?level?than?the?points?(P<0.01),?the?detection?rate?in?the?diabetic?group?showed?no?significant?differences?(P>0.05),?serum?glycated?albumin?was?significantly?correlated?with?the?glycosylated?hemoglobin?(r=0.75,?P<0.01),?fasting?blood?glucose,?blood?glucose?2H?and?BMI?as?independent?factors?affecting?serum?glycated?albumin;?Conclusion?Glycated?serum?albumin?determination?for?the?diagnosis?of?diabetes,?treatment?effect?and?the?treatment?plan?may?make?sense.