中外医疗
中外醫療
중외의료
CHINA FOREIGN MEDICAL TREATMENT
2015年
8期
8-9
,共2页
肺炎支原体性肺炎%小儿%红霉素%阿奇霉素%肿瘤坏死因子-α
肺炎支原體性肺炎%小兒%紅黴素%阿奇黴素%腫瘤壞死因子-α
폐염지원체성폐염%소인%홍매소%아기매소%종류배사인자-α
Mycoplasma pneumoniae pneumonia%Children%Erythromycin%Azithromycin%Tumor necrosis factor-α
目的：探讨肺炎支原体性肺炎患儿采用红霉素与阿奇霉素治疗对血清肿瘤坏死因子-α（tumor necrosis factor-α，TNF-α）水平的影响。方法从该院2013年9月—2014年9月收治的肺炎支原体性肺炎患儿中随机选择77例进行研究，按治疗方法分为对照组（38例）和观察组（39例），分别给予红霉素治疗和阿奇霉素治疗。观察两组的治疗效果和治疗前后的TNF-α水平变化情况，并进行分析。结果观察组的治疗总有效率显著高于对照组，两组的TNF-α水平治疗前比较差异无统计学意义，两组的TNF-α水平治疗后比较差异有统计学意义，观察组显著低于对照组（P＜0.05）。结论利用阿奇霉素治疗肺炎支原体性肺炎患儿可以获得良好的效果，并有效降低其血清TNF-α水平。
目的：探討肺炎支原體性肺炎患兒採用紅黴素與阿奇黴素治療對血清腫瘤壞死因子-α（tumor necrosis factor-α，TNF-α）水平的影響。方法從該院2013年9月—2014年9月收治的肺炎支原體性肺炎患兒中隨機選擇77例進行研究，按治療方法分為對照組（38例）和觀察組（39例），分彆給予紅黴素治療和阿奇黴素治療。觀察兩組的治療效果和治療前後的TNF-α水平變化情況，併進行分析。結果觀察組的治療總有效率顯著高于對照組，兩組的TNF-α水平治療前比較差異無統計學意義，兩組的TNF-α水平治療後比較差異有統計學意義，觀察組顯著低于對照組（P＜0.05）。結論利用阿奇黴素治療肺炎支原體性肺炎患兒可以穫得良好的效果，併有效降低其血清TNF-α水平。
목적：탐토폐염지원체성폐염환인채용홍매소여아기매소치료대혈청종류배사인자-α（tumor necrosis factor-α，TNF-α）수평적영향。방법종해원2013년9월—2014년9월수치적폐염지원체성폐염환인중수궤선택77례진행연구，안치료방법분위대조조（38례）화관찰조（39례），분별급여홍매소치료화아기매소치료。관찰량조적치료효과화치료전후적TNF-α수평변화정황，병진행분석。결과관찰조적치료총유효솔현저고우대조조，량조적TNF-α수평치료전비교차이무통계학의의，량조적TNF-α수평치료후비교차이유통계학의의，관찰조현저저우대조조（P＜0.05）。결론이용아기매소치료폐염지원체성폐염환인가이획득량호적효과，병유효강저기혈청TNF-α수평。
Objective To explore the effect of erythromycin and azithromycin on the level of serum tumor necrosis factor-α (TNF-α) of children with mycoplasma pneumoniae pneumonia. Methods Seventy-seven children with mycoplasma pneumoniae pneumo-nia admitted in our hospital from September 2013 to September 2014 were randomly selected and divided into the control group (38 cases) and observation group (39 cases) according to the treartment method, and treated by erythromycin, azithromycin, respec-tively. The treatment effect and level of TNF-α before and after the treatment of the two groups were observed and analyzed. Re-sults The overall response rate of the observation group was much higher than that of the control group. Before treatment, the dif-ference in the level of TNF-α between the two groups was not statistically significant, but after treatment, the level of TNF-α of the observation group was much lower than that of the control group, the difference between the two groups was statistically signifi-cant(P<0.05). Conclusion Azithromycin in the treatment of children with mycoplasma pneumoniae pneumonia can obtain good ef-fect, which can effectively reduce the level of serum TNF-α.
