CAJ | 학술논문

目的：探讨急性心肌梗死患者经皮冠状动脉介入治疗（PCI）中联合应用血栓抽吸和替罗非班的效果。方法随机选取该院2011年1月—2014年6月间收治的急性心肌梗死患者84例，均行PCI术，随机分为对照组（应用替罗非班）和观察组（同时应用替罗非班和血栓抽吸），比较两组治疗效果。结果观察组患者PCI术后冠脉造影TIMI 3级血流获得率明显高于对照组，术后3个月患者心功能优于对照组；随访6个月患者术后心血管事件发生率（0.0%）明显低于对照组（14.29%），差异有统计学意义（P＜0.05）。结论急性心肌梗死介入治疗中联合应用血栓抽吸和替罗非班效果显著，值得临床推广应用。
목적：탐토급성심기경사환자경피관상동맥개입치료（PCI）중연합응용혈전추흡화체라비반적효과。방법수궤선취해원2011년1월—2014년6월간수치적급성심기경사환자84례，균행PCI술，수궤분위대조조（응용체라비반）화관찰조（동시응용체라비반화혈전추흡），비교량조치료효과。결과관찰조환자PCI술후관맥조영TIMI 3급혈류획득솔명현고우대조조，술후3개월환자심공능우우대조조；수방6개월환자술후심혈관사건발생솔（0.0%）명현저우대조조（14.29%），차이유통계학의의（P＜0.05）。결론급성심기경사개입치료중연합응용혈전추흡화체라비반효과현저，치득림상추엄응용。
Objective To investigate the effect of thrombus aspiration combined with tirofiban on acute myocardial infarction(AMI) with percutaneous coronary intervention (PCI). Methods 84 cases with AMI underwent PCI in our hospital from January 2011 to June 2014 were randomly divided into the control group treated by tirofiban and the observation group treated by tirofiban and thrombus aspiration. And the treatment effect was compared between the two groups. Results The coronary angiography after PCI showed that, a greater percentage of TIMI 3 flow was achieved in the observation group compared with the control group; the ob-servation group had better cardiac function 3 months after the surgery than the control group; the incidence of postoperative car-diovascular event of the observation group was much lower than that of the control group showed by the 6-month follow-up(0.0%vs. 14.29%), the differences were statistically significant (P<0.05). Conclusion The combined application of thrombus aspiration and tirofiban to AMI with PIC has significant effect, which is worthy of clinical application and promotion.