中外医疗
中外醫療
중외의료
CHINA FOREIGN MEDICAL TREATMENT
2015年
8期
60-61
,共2页
连续性肾脏替代疗法%不同容量%腹腔感染
連續性腎髒替代療法%不同容量%腹腔感染
련속성신장체대요법%불동용량%복강감염
Continuous renal replacement therapy%Different capacity%Abdominal infection
目的:研究在治疗严重腹腔感染时不同血液滤过量连续性肾脏替代治疗的对比情况。方法该研究选取2012年1月—2013年12月间该院收治的60例患者为研究对象,将60例患者平均分成两组,分别对其采取常规血液滤过量,作为常规容量组;大容量持续连续性肾脏替代治疗,作为大容量组。分别治疗前后4h、12h、24h、36h、48h、72h6个时间段血浆肿瘤坏死因子-α(TNF-α)、白介素-6(IL-6)水平及降钙素原(PCT)水平,并统计其ICU入住时间、机械通气时间、日均医疗费用。结果施用大量容量持续连续性肾脏替代治疗的小组,其治疗后4~48 h之间TNF-α、IL-6水平下降明显,之后没有明显下降,而PCT则在4~72 h一直处于下降状态。经过统计后,大容量小组ICU入住时间、机械通气时间均短于常规容量小组,而日均医疗费用两组之间无明显差距。结论在费用基本相同的情况下,利用较大血液滤过量连续性肾脏替代法可以有效缓解腹腔感染症状,值得在临床实践中进行推广。
目的:研究在治療嚴重腹腔感染時不同血液濾過量連續性腎髒替代治療的對比情況。方法該研究選取2012年1月—2013年12月間該院收治的60例患者為研究對象,將60例患者平均分成兩組,分彆對其採取常規血液濾過量,作為常規容量組;大容量持續連續性腎髒替代治療,作為大容量組。分彆治療前後4h、12h、24h、36h、48h、72h6箇時間段血漿腫瘤壞死因子-α(TNF-α)、白介素-6(IL-6)水平及降鈣素原(PCT)水平,併統計其ICU入住時間、機械通氣時間、日均醫療費用。結果施用大量容量持續連續性腎髒替代治療的小組,其治療後4~48 h之間TNF-α、IL-6水平下降明顯,之後沒有明顯下降,而PCT則在4~72 h一直處于下降狀態。經過統計後,大容量小組ICU入住時間、機械通氣時間均短于常規容量小組,而日均醫療費用兩組之間無明顯差距。結論在費用基本相同的情況下,利用較大血液濾過量連續性腎髒替代法可以有效緩解腹腔感染癥狀,值得在臨床實踐中進行推廣。
목적:연구재치료엄중복강감염시불동혈액려과량련속성신장체대치료적대비정황。방법해연구선취2012년1월—2013년12월간해원수치적60례환자위연구대상,장60례환자평균분성량조,분별대기채취상규혈액려과량,작위상규용량조;대용량지속련속성신장체대치료,작위대용량조。분별치료전후4h、12h、24h、36h、48h、72h6개시간단혈장종류배사인자-α(TNF-α)、백개소-6(IL-6)수평급강개소원(PCT)수평,병통계기ICU입주시간、궤계통기시간、일균의료비용。결과시용대량용량지속련속성신장체대치료적소조,기치료후4~48 h지간TNF-α、IL-6수평하강명현,지후몰유명현하강,이PCT칙재4~72 h일직처우하강상태。경과통계후,대용량소조ICU입주시간、궤계통기시간균단우상규용량소조,이일균의료비용량조지간무명현차거。결론재비용기본상동적정황하,이용교대혈액려과량련속성신장체대법가이유효완해복강감염증상,치득재림상실천중진행추엄。
Objective Comparison study of different in the treatment of severe abdominal infection hemofiltration quantity in con-tinuous renal replacement therapy. Methods 40 patients were divided into two groups.Respectively to take excessive, large capaci-ty of conventional filter blood continuously continuous renal replacement therapy.Respectively before and after treatment 4 h ,12 h, 24 h, 36 h, 48 h, 72 h six time of plasma tumor necrosis factor alpha(TNF- α), interleukin-6(IL-6) and the of procalcitonin (PCT) level.And statistics of their ICU stay, mechanical ventilation time, average medical expenses. Result Large capacity continuous application of continuous renal replacement therapy group.The after treatment between 4~48 h TNF-α, IL-6 levels decreased significantly, after no obvious decline.PCT in 4~72 h has been in a state of decline.After statistics, large capacity ICU group check-in time, me-chanical ventilation time were shorter than the normal capacity of group, and the daily average medical expenses between the two groups had no significant difference. Conclusion In the same basic cost, using large volume hemofiltration continuous renal replacement method can be effective in the treatment of abdominal infection symptoms, and it is worthy to popularize in clinical practice.