CAJ | 학술논문

目的：：通过对重庆市精神病院36例精神分裂症患者追踪分析,以研究眼球运动轨迹与精神分裂症之间的关系。方法：抽取使用眼动分析仪筛查出36例D值为正分的精神分裂症患者作为研究组,对患者进行眼动分析仪对比追踪分析研究；另选取健康人36例作为对照组。结果：经对照分析,0周研究组患者与对照组研究对象各项眼动测定值比较有显著性差异(P<0.01)；研究组患者治疗8周前后各项眼动测定值比较差异无统计学意义(P>0.05)；研究组患者治疗8周后不同精神状态各项眼动测定值比较差异无统计学意义(P>0.05)。结论：提示精神分裂症患者眼动异常特别是眼注视点(number of eye fixation, NEF)、反应性探究分(responsive of search scores, RSS)的改变对疾病诊断最有特征性意义,与年龄、性别、临床精神状态无关,而传统与非传统抗精神病药物治疗对眼动测定值无影响,据此推测精神分裂症患者眼动异常可能不是状态学指标而是一种生物学指征,可以作为临床上精神分裂症有价值的辅助诊断依据。
목적：：통과대중경시정신병원36례정신분렬증환자추종분석,이연구안구운동궤적여정신분렬증지간적관계。방법：추취사용안동분석의사사출36례D치위정분적정신분렬증환자작위연구조,대환자진행안동분석의대비추종분석연구；령선취건강인36례작위대조조。결과：경대조분석,0주연구조환자여대조조연구대상각항안동측정치비교유현저성차이(P<0.01)；연구조환자치료8주전후각항안동측정치비교차이무통계학의의(P>0.05)；연구조환자치료8주후불동정신상태각항안동측정치비교차이무통계학의의(P>0.05)。결론：제시정신분렬증환자안동이상특별시안주시점(number of eye fixation, NEF)、반응성탐구분(responsive of search scores, RSS)적개변대질병진단최유특정성의의,여년령、성별、림상정신상태무관,이전통여비전통항정신병약물치료대안동측정치무영향,거차추측정신분렬증환자안동이상가능불시상태학지표이시일충생물학지정,가이작위림상상정신분렬증유개치적보조진단의거。
Objective:To study relationships among eye movements and schizophrenia through tracking analysis of 36 patients with schizophrenia. Methods:36 schizophrenic patients with D value screened with an eye movement analyzed were chosen as study group for the comparative tracking analysis, while 36 healthy people were selected as control group. Results:Through the contrast a-nalysis, there were statistically significant differences in each eye movement measurement value at 0 weeks between study group and control group (P<0. 001). There were no statistically significant differences in each eye movement measurement value in study group before and 8 weeks after the treatment (P>0. 05), and so did the each eye movement measurement value among the patients with dif-ferent mental states in study group before and 8 weeks after the treatment (P>0. 05). Conclusions:Abnormal eye movements, espe-cially the changes of NEF and RSS, have the most characteristic significance in the diagnosis of the disease, and are not related with age, sex and clinical mental status. Due to no effects of traditional and non-traditional antipsychotic drugs on the measured eye move-ment value, it is supposed that the abnormal eye movements may not be a status indicator but a biological indicator, and can be a valu-able auxiliary diagnosis basis for schizophrenia in the clinic.