CAJ | 학술논문

目的：探讨溃疡性结肠炎的临床特征及结肠镜下表现。方法：回顾分析天津市人民医院2008年1月—2013年6月经结肠镜检查和病理确诊的2869例溃疡性结肠炎患者的临床资料，分析临床特征，结肠镜下表现和病理诊断结果。结果：溃疡性结肠炎患者2869例，男性1593例，女性1276例，男女之比1.25∶1。年龄为10~78岁，平均43.5岁，40~49岁患病率最高。临床主要表现为腹泻、粘液脓血便和不同程度的腹痛，其中腹泻发生率最高，为78.67%，粘液脓血便发生率为62.22%，腹痛为44.06%，里急后重为30.88%。病变累及直肠的为1354例，占47.19%；累及直肠、乙状结肠者为684例，占23.84%；病变位为左半结肠者324例，占11.29%；广泛结肠受累222例，占7.74%；病变为全结肠者285例，占9.94%。结肠镜下主要表现为肠黏膜弥漫性充血水肿、糜烂或伴溃疡形成。结肠镜诊断溃疡性结肠炎的准确率为95%。结论：结肠镜结合病理检查对溃疡性结肠炎的诊断具有重要的临床价值。
목적：탐토궤양성결장염적림상특정급결장경하표현。방법：회고분석천진시인민의원2008년1월—2013년6월경결장경검사화병리학진적2869례궤양성결장염환자적림상자료，분석림상특정，결장경하표현화병리진단결과。결과：궤양성결장염환자2869례，남성1593례，녀성1276례，남녀지비1.25∶1。년령위10~78세，평균43.5세，40~49세환병솔최고。림상주요표현위복사、점액농혈편화불동정도적복통，기중복사발생솔최고，위78.67%，점액농혈편발생솔위62.22%，복통위44.06%，리급후중위30.88%。병변루급직장적위1354례，점47.19%；루급직장、을상결장자위684례，점23.84%；병변위위좌반결장자324례，점11.29%；엄범결장수루222례，점7.74%；병변위전결장자285례，점9.94%。결장경하주요표현위장점막미만성충혈수종、미란혹반궤양형성。결장경진단궤양성결장염적준학솔위95%。결론：결장경결합병리검사대궤양성결장염적진단구유중요적림상개치。
Objective To investigate the clinical and colonoscopic features of ulcerative colitis (UC). Methods The clinical data obtained from 2869 patients with UC were retrospectively analyzed for UC charac?teristics and colonoscopic manifestations and pathologic diagnosis. Results Among 2869 cases, 1593 were male, and 1276 female. The ratio of male to female was 1.25∶1.The mean age was 43.5 years (range 10~78 years, mostly within 40~49). The duration of the disease was between 1 month to 20 years. The most common clinical manifestations were diarrhea, bloody purulent stool and abdominal pain. The common colonoscopic findings were diffused congestive edema of intestinal mucosa, or widespread erythema, erosion and ulceration. The correct diag?nostic rate of colonoscopy was 95%. Conclusion Colonoscopy combined with biopsy plays an important role in the diagnosis of ulcerative colitis and may improve diagnostic sensitivity.