临床与实验病理学杂志
臨床與實驗病理學雜誌
림상여실험병이학잡지
CHINESE JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY
2015年
3期
298-301
,共4页
颅内肿瘤%儿童%临床病理分析
顱內腫瘤%兒童%臨床病理分析
로내종류%인동%림상병리분석
intracranial neoplasm%children%clinicopathological analysis
目的：探讨儿童颅内肿瘤的临床病理学特征。方法对221例经外科手术切除、病理确诊的儿童(18岁及其以下)颅内肿瘤进行回顾性分析,并复习相关文献。结果本组病例占同期颅内肿瘤的7．21%,男女比为1．06∶1,男性患儿稍多。3岁以下患儿较少,其余各年龄组病例数大致相当。最常见首发症状为呕吐、头昏头痛、共济失调。发病部位：幕上153例(69．23%),幕下68例(30．77%)。幕上最常见为大脑半球和鞍区,幕下为小脑和第四脑室。 WHOⅠ级或良性肿瘤89例,占40．27%；恶性肿瘤132例,占59．73%,其中WHO Ⅳ级或其他高度恶性肿瘤61例,占27．60%。发病率位居前5位的肿瘤分别为星形细胞瘤、胚胎性肿瘤、颅咽管瘤、室管膜瘤、生殖细胞瘤。星形细胞瘤中弥漫型星形细胞瘤和毛细胞星形细胞瘤多见,高级别星形细胞瘤少见。胚胎性肿瘤中髓母细胞瘤和幕上原始神经外胚层肿瘤多见。结论儿童颅内肿瘤发病率逐年增高,病理类型多样,恶性居多,正确诊断非常重要。
目的：探討兒童顱內腫瘤的臨床病理學特徵。方法對221例經外科手術切除、病理確診的兒童(18歲及其以下)顱內腫瘤進行迴顧性分析,併複習相關文獻。結果本組病例佔同期顱內腫瘤的7．21%,男女比為1．06∶1,男性患兒稍多。3歲以下患兒較少,其餘各年齡組病例數大緻相噹。最常見首髮癥狀為嘔吐、頭昏頭痛、共濟失調。髮病部位：幕上153例(69．23%),幕下68例(30．77%)。幕上最常見為大腦半毬和鞍區,幕下為小腦和第四腦室。 WHOⅠ級或良性腫瘤89例,佔40．27%；噁性腫瘤132例,佔59．73%,其中WHO Ⅳ級或其他高度噁性腫瘤61例,佔27．60%。髮病率位居前5位的腫瘤分彆為星形細胞瘤、胚胎性腫瘤、顱嚥管瘤、室管膜瘤、生殖細胞瘤。星形細胞瘤中瀰漫型星形細胞瘤和毛細胞星形細胞瘤多見,高級彆星形細胞瘤少見。胚胎性腫瘤中髓母細胞瘤和幕上原始神經外胚層腫瘤多見。結論兒童顱內腫瘤髮病率逐年增高,病理類型多樣,噁性居多,正確診斷非常重要。
목적：탐토인동로내종류적림상병이학특정。방법대221례경외과수술절제、병리학진적인동(18세급기이하)로내종류진행회고성분석,병복습상관문헌。결과본조병례점동기로내종류적7．21%,남녀비위1．06∶1,남성환인초다。3세이하환인교소,기여각년령조병례수대치상당。최상견수발증상위구토、두혼두통、공제실조。발병부위：막상153례(69．23%),막하68례(30．77%)。막상최상견위대뇌반구화안구,막하위소뇌화제사뇌실。 WHOⅠ급혹량성종류89례,점40．27%；악성종류132례,점59．73%,기중WHO Ⅳ급혹기타고도악성종류61례,점27．60%。발병솔위거전5위적종류분별위성형세포류、배태성종류、로인관류、실관막류、생식세포류。성형세포류중미만형성형세포류화모세포성형세포류다견,고급별성형세포류소견。배태성종류중수모세포류화막상원시신경외배층종류다견。결론인동로내종류발병솔축년증고,병리류형다양,악성거다,정학진단비상중요。
Purpose To analyze the clinical and pathological features of intracranial tumor in children. Methods 221 cases of in-tracranial tumors in children ( ages≤18 years) were retrospectively analyzed. Results The cases of intracranial tumor in children ac-counted for 7. 21% of total cases in our hospital during the same period. There is no documented gender bias. There were only 14 cases (6. 33%) with age less than 3 years old. The supratentorial tumors were 153 cases (69. 23%) and infratentorial tumors were 68 cases (30. 77%) . The most frequently affected sites were the cerebral hemispherse, sellar region, vermis and the fourth ventricle. There were 89 benign tumor and 132 malignant tumor in this series of cases. The most common five tumors were astrocytic tumors (30. 32%), embryonal tumors (19. 00%), craniopharyngiomas (11. 76%), ependymal tumors (8. 14%) and germ cell tumors (5. 88%). Conclusion The morbidity of intracranial tumors in children has increased in the recent years. The histological classifica-tion of intracranial tumors in children is multiple and it is essential to make a correct diagnosis.
