CAJ | 학술논문

目的：通过MRI壳核面积测量为纹状体黑质变性（SND）和帕金森病（PD）两种临床容易混淆的疾病提供了一个可靠的鉴别方法。方法回顾性分析经临床诊断为SND 9例，PD17例和正常人17例常规磁共振成像资料，通过MRI对壳核面积进行测量。结果 SND患者的壳核面积较PD患者及正常组均显著降低（ P﹤0．05），而PD患者和正常组壳核面积差别无显著意义。SND主要表现为在T2加权像可见壳核边缘高信号和壳核萎缩，部分患者可见桥脑十字征。轴位T1加权像可见小脑中脚萎缩等M RI表现，矢状位T1加权像可见小脑、桥脑和延髓萎缩等M RI表现。结论M RI壳核面积测量有助于SND和PD两种疾病的鉴别诊断。
목적：통과MRI각핵면적측량위문상체흑질변성（SND）화파금삼병（PD）량충림상용역혼효적질병제공료일개가고적감별방법。방법회고성분석경림상진단위SND 9례，PD17례화정상인17례상규자공진성상자료，통과MRI대각핵면적진행측량。결과 SND환자적각핵면적교PD환자급정상조균현저강저（ P﹤0．05），이PD환자화정상조각핵면적차별무현저의의。SND주요표현위재T2가권상가견각핵변연고신호화각핵위축，부분환자가견교뇌십자정。축위T1가권상가견소뇌중각위축등M RI표현，시상위T1가권상가견소뇌、교뇌화연수위축등M RI표현。결론M RI각핵면적측량유조우SND화PD량충질병적감별진단。
Objective We have provided a reliable differential diagnosis for the striatonigral degeneration (SND) and Parkinson disease (PD) that are easy to confuse disease in clinical diagnosis by MRI measurement .Methods The clinical diagnosis for the SND of 9 cases ,PD of 17 cases and 17 normal cases of conventional magnetic resonance imaging data are retrospectively analyzed .Putamen area have been measured by the method of measuring the M RI .Results Putamen area is statistically significant ( P﹤0 .05) to be found compared with PD group and control group .But the PD group and con‐trol group have no statistically significant difference in the putamen area .The main MRI findings of SND are hyperintense rim of putamen and putaminal atrophy .The cross sign of the T2 WI is found in the few SND patiens .The cerebellar atro‐phy ,atrophy of middle cerebellar peduncles ,medulla oblongata atrophy and pontine atrophy are found in the few SND pa‐tiens .Conclusion M RI measurements of the putamen area helps in the differential diagnosis of SND and PD .