CAJ | 학술논문

天然多糖海藻酸钠制备的水凝胶具有优越的生物相容性和生物组织相似性，作为生物医用材料在药物控制释放、组织工程支架、抗菌材料及创伤敷料等领域发挥着越来越大的作用。本文在介绍海藻酸钠物化性质的基础上，重点综述了非共价键交联(静电作用、氢键、范德华力、亲疏水作用等)海藻酸钠水凝胶的制备方法以及性能表征方法，最后讨论了制备方法及性能表征研究中的一些需要解决的问题。
천연다당해조산납제비적수응효구유우월적생물상용성화생물조직상사성，작위생물의용재료재약물공제석방、조직공정지가、항균재료급창상부료등영역발휘착월래월대적작용。본문재개소해조산납물화성질적기출상，중점종술료비공개건교련(정전작용、경건、범덕화력、친소수작용등)해조산납수응효적제비방법이급성능표정방법，최후토론료제비방법급성능표정연구중적일사수요해결적문제。
Sodium alginate hydrogel has been widely used as biomedical materials in drug delivery system, tissue engineering scaffolds, antibacterial material and wound dressing, due to their superior biocompatibility and resemblance to biological tissues. Based on the brief introduction of physicochemical properties of sodium alginate, the progress in preparation methods of sodium alginate hydrogel crosslinked by non-covalent bonds is summarized including electrostatic interaction, hydrogen bonds, van der Waals forces and hydrophobic effects, etc. Meantime, the characterization methods of properties of sodium alginate hydrogel are also concerned. Finally, some problems related to the development of preparation and characterization methods are discussed.