CAJ | 학술논문

目的：观察慢性肾脏病（chronic kidney disease，CKD）患者外周血中锶水平的变化。方法测定254例CKD 患者与40例健康体检者血清锶含量。结果根据肌酐清除率将 CKD 患者分为4组，各组血清锶水平均明显高于对照组（P ＜0．01），但 CKD 患者组间比较差异无统计学意义（P ＞0．05）。通过 ROC 曲线获得锶预测 CKD 的临界值为40．25μg／L。结论 CKD 患者易引起锶的蓄积，锶水平可能对 CKD 的早期筛查有积极意义。
목적：관찰만성신장병（chronic kidney disease，CKD）환자외주혈중송수평적변화。방법측정254례CKD 환자여40례건강체검자혈청송함량。결과근거기항청제솔장 CKD 환자분위4조，각조혈청송수평균명현고우대조조（P ＜0．01），단 CKD 환자조간비교차이무통계학의의（P ＞0．05）。통과 ROC 곡선획득송예측 CKD 적림계치위40．25μg／L。결론 CKD 환자역인기송적축적，송수평가능대 CKD 적조기사사유적겁의의。
Objective To study strontium change of patients with chronic kidney disease (CKD).Methods The serum strontium was measured in 254 CKD patients and 40 healthy volunteers.Results According to creatinine clearance rate,CKD patients were divided into four groups,the serum strontium levels of different groups of CKD patients were significantly higher than that of control group(P <0.01),but there were no significant difference between the groups of CKD patients(P >0.05).ROC curve was 40.25 μg/L for serum strontium to predict the critical value of CKD.Conclusion Patients with CKD can lead to the accumulation of strontium;Strontium level may have a positive meaning for the early screening of CKD.