CAJ | 학술논문

目的：通过检测血清中血管内皮生长因子的水平，以研究其在消化系统肿瘤中表达的意义。方法选取2011年2月～2014年12月入我院经临床确诊的100例消化系统肿瘤患者为观察组，100例正常者为对照组。检测两组患者血清血管内皮生长因子的含量及表达阳性率，并分析比较检测结果。结果观察组和对照组的血管内皮生长因子水平分别为（515.2±180.3）ng/L、（180.5±85.8）ng/L，观察组明显高于对照组，两组相比较差别具有统计学意义（P＜0.05）。结论血清中血管内皮生长因子含量检测对消化系统肿瘤疾病的预后及治疗有着重要的临床意义。
목적：통과검측혈청중혈관내피생장인자적수평，이연구기재소화계통종류중표체적의의。방법선취2011년2월～2014년12월입아원경림상학진적100례소화계통종류환자위관찰조，100례정상자위대조조。검측량조환자혈청혈관내피생장인자적함량급표체양성솔，병분석비교검측결과。결과관찰조화대조조적혈관내피생장인자수평분별위（515.2±180.3）ng/L、（180.5±85.8）ng/L，관찰조명현고우대조조，량조상비교차별구유통계학의의（P＜0.05）。결론혈청중혈관내피생장인자함량검측대소화계통종류질병적예후급치료유착중요적림상의의。
Objective To investigate the change of vascular endothelial growth factor (VEGF) in serum of the patients with malignant tumor of digestive system and the correlation with the initiation and development of malignant tumor of digestive system.Methods Select February 2011~December 2014 into the hospital clinically diagnosed 100 cases of digestive system cancer patients in the observation group, 100 cases of normal control group. Two groups of patients serum vascular endothelial growth factor content and expression rate, and the analysis and comparison of test results.Results Observation group and the control group of vascular endothelial growth factor levels were (515.2 ± 180.3) ng / L, (180.5 ± 85.8) ng / L, the observation group was signiifcantly higher than control subject (P<0.05).Conclusion The detection of VEGF in serum is of great signiifcance to the diagnosis and prognosis of malignant tumor of digestive system.