CAJ | 학술논문

目的：回顾性分析准分子激光角膜屈光术后早期角膜感染的诊断与治疗策略及视力转归。方法对2008年1月至2014年3月我院收治的因准分子激光术后早期角膜感染患者7例（8只眼）进行回顾性分析。根据患者病史、共焦显微镜或角膜病灶组织刮片等检查明确其感染类型，对症采用局部及全身药物治疗，对药物不能控制的感染采取手术治疗，并观察视力转归情况。结果患者8只眼全部诊断为细菌性角膜溃疡，其中8只眼病灶组织刮片检查为阳性，5只眼细菌培养阳性。4只眼（50．0％）经抗菌药物治疗达到溃疡愈合，4只眼（50．0％）行板层性角膜移植术治愈。治愈病例至溃疡愈合时，8只眼视力均较治疗前提高。结论感染性角膜炎是准分子激光术后早期发生的严重并发症，尽早明确诊断并积极治疗是控制感染、保存视力的关键。
목적：회고성분석준분자격광각막굴광술후조기각막감염적진단여치료책략급시력전귀。방법대2008년1월지2014년3월아원수치적인준분자격광술후조기각막감염환자7례（8지안）진행회고성분석。근거환자병사、공초현미경혹각막병조조직괄편등검사명학기감염류형，대증채용국부급전신약물치료，대약물불능공제적감염채취수술치료，병관찰시력전귀정황。결과환자8지안전부진단위세균성각막궤양，기중8지안병조조직괄편검사위양성，5지안세균배양양성。4지안（50．0％）경항균약물치료체도궤양유합，4지안（50．0％）행판층성각막이식술치유。치유병례지궤양유합시，8지안시력균교치료전제고。결론감염성각막염시준분자격광술후조기발생적엄중병발증，진조명학진단병적겁치료시공제감염、보존시력적관건。
Objective Retrospective analysis of diagnosis and treatment strategies and visual acuity outcomes of the early corneal infection after excimer laser cornea refractive surgery.Methods Retrospective analysis 7 patients 8 eyes early postoperative corneal infection after excimer laser who treated in our hospital in 2008 January to 2014 March.Confirm the type of infection according to patient history, confocal microscopy or corneal tissue scraping test , using local and sys-temic drug treatment, take the operation if drug can not control the infection, and observe the visual prognosis.Results All patients with 8 eyes diagnosed as bacterial corneal ulcer, 8 eyes Lesions tissue smear examination, 5 eyes of bacterial culture were positive.4 eyes (50%) after anti bacteria drug treatment to the healing of ulcer, 4 eyes (50%) taking lamel-lar keratoplasty to cure.To the healing of ulcers, visual acuity of 8 eyes was improved compared with those before treat-ment.Conclusion Infective keratitis is a severe complication occ-urred after excimer laser refractive surgery, the key to control inf-ection, save sight is diagnosis and aggressive treatment as soon as possible.