健康研究
健康研究
건강연구
HEALTH RESEARCH
2015年
2期
161-163
,共3页
复方甘草酸苷%非索非那定片%慢性湿疹
複方甘草痠苷%非索非那定片%慢性濕疹
복방감초산감%비색비나정편%만성습진
compound glycyrrhizin%fexofenadine%chronic eczema
目的：探讨复方甘草酸苷联合非索非那定片对慢性湿疹的临床疗效。方法80例慢性湿疹患者随机分为观察组和对照组各40例，对照组患者口服非索非那定片，观察组患者在对照组基础上加服复方甘草酸苷片，均连续治疗8周。观察两组患者临床疗效，比较两组患者治疗前后症状评分、DQOLS评分，随访复发情况以及治疗期间的不良反应发生情况。结果观察组治疗总有效率（87．50％）高于对照组（67．50％），差异具有统计学意义（P＜0.05）；治疗后两组患者症状评分以及DQOLS评分均较治疗前显著改善（P＜0．05），且观察组改善情况显著优于对照组（P＜0．05）；在停药4周、停药8周以及停药12周两组复发率比较上，观察组均显著低于对照组（P＜0．05）。结论复方甘草酸苷联合非索非那定片治疗慢性湿疹疗效显著，复发率低，且有效改善患者生活质量。
目的：探討複方甘草痠苷聯閤非索非那定片對慢性濕疹的臨床療效。方法80例慢性濕疹患者隨機分為觀察組和對照組各40例，對照組患者口服非索非那定片，觀察組患者在對照組基礎上加服複方甘草痠苷片，均連續治療8週。觀察兩組患者臨床療效，比較兩組患者治療前後癥狀評分、DQOLS評分，隨訪複髮情況以及治療期間的不良反應髮生情況。結果觀察組治療總有效率（87．50％）高于對照組（67．50％），差異具有統計學意義（P＜0.05）；治療後兩組患者癥狀評分以及DQOLS評分均較治療前顯著改善（P＜0．05），且觀察組改善情況顯著優于對照組（P＜0．05）；在停藥4週、停藥8週以及停藥12週兩組複髮率比較上，觀察組均顯著低于對照組（P＜0．05）。結論複方甘草痠苷聯閤非索非那定片治療慢性濕疹療效顯著，複髮率低，且有效改善患者生活質量。
목적：탐토복방감초산감연합비색비나정편대만성습진적림상료효。방법80례만성습진환자수궤분위관찰조화대조조각40례，대조조환자구복비색비나정편，관찰조환자재대조조기출상가복복방감초산감편，균련속치료8주。관찰량조환자림상료효，비교량조환자치료전후증상평분、DQOLS평분，수방복발정황이급치료기간적불량반응발생정황。결과관찰조치료총유효솔（87．50％）고우대조조（67．50％），차이구유통계학의의（P＜0.05）；치료후량조환자증상평분이급DQOLS평분균교치료전현저개선（P＜0．05），차관찰조개선정황현저우우대조조（P＜0．05）；재정약4주、정약8주이급정약12주량조복발솔비교상，관찰조균현저저우대조조（P＜0．05）。결론복방감초산감연합비색비나정편치료만성습진료효현저，복발솔저，차유효개선환자생활질량。
Objective To examine the medicinal effect of Compound Glycyrrhizin combined with fexofenadine in treating chronic eczema.Method 80 patients were randomly divided into an experimental group (n=40) and a control group (n=40) .The control group were treated with oral fexofenadine while the experimental group were treated with Compound Glycyrrhizin in addition to fexofenadine for a period of eight weeks.The effects of the medicines were then observed.The DQOLS scores of the two groups were next compared, and follow-ups were conducted for recurrence and side effects. Findings The total effective rate of the experimental group (87.50%) was significantly higher than that of the control group ( 67.50%).The difference was statistically significant (P<0.05).After treatment both groups achieved higher symptom score and DQOLS score (P<0.05), with the experimental group achieving an even higher score than the control group (P<0.05).The recurrence rate of the experimental group was lower than that of the control group as observed 4 weeks, 8 weeks, and 12 weeks after withdrawal of medicine ( P <0.05 ) .Conclusion Compound Glycyrrhizin combined with fexofenadine can serve as an effective medicine for the disease of chronic eczema.The medicine can considerably contribute to the quality of a patient's life as it results in low rate of recurrence of the disease.
