实用癌症杂志
實用癌癥雜誌
실용암증잡지
THE PRACTICAL JOURNAL OF CANCER
2015年
4期
553-555
,共3页
淋巴结转移度%大肠癌%远处转移%预后
淋巴結轉移度%大腸癌%遠處轉移%預後
림파결전이도%대장암%원처전이%예후
Lymph node ratio%Colorectal cancer%Distant metastasis%Prognosis
目的：探讨淋巴结转移度（ LNR）对Ⅲ期大肠癌患者发生远处转移的预测效果。方法将进行根治性切除手术的55例Ⅲ期大肠癌患者依据LNR分为2组：低LNR组（LNR＜0．167）和高LNR组（LNR≥0．167）；分析LNR与大肠癌术后出现远处转移的关系。结果低LNR组（29例，52．7％）中未发生远处转移的患者19例（65．5％），发生远处转移的患者10例（34．5％）；高LNR组（26例，47．3％）中未发生远处转移的患者11例（42．3％），发生远处转移的患者15例（57．7％）。高LNR组较低LNR组的大肠癌患者更容易发生远处转移；在发生远处转移的患者中，肝转移有15例，肺转移有6例，骨及多脏器转移有4例。多因素分析结果表明LNR、肿瘤类型及分化程度均是影响大肠癌发生远处转移的独立相关因素（ RR：1．999；CI％：1．101～4．092；P＝0．029）。结论 LNR与大肠癌术后发生远处转移构成独立相关，可与肿瘤类型、分化程度等作为评估大肠癌术后发生远处转移的参考指标。
目的：探討淋巴結轉移度（ LNR）對Ⅲ期大腸癌患者髮生遠處轉移的預測效果。方法將進行根治性切除手術的55例Ⅲ期大腸癌患者依據LNR分為2組：低LNR組（LNR＜0．167）和高LNR組（LNR≥0．167）；分析LNR與大腸癌術後齣現遠處轉移的關繫。結果低LNR組（29例，52．7％）中未髮生遠處轉移的患者19例（65．5％），髮生遠處轉移的患者10例（34．5％）；高LNR組（26例，47．3％）中未髮生遠處轉移的患者11例（42．3％），髮生遠處轉移的患者15例（57．7％）。高LNR組較低LNR組的大腸癌患者更容易髮生遠處轉移；在髮生遠處轉移的患者中，肝轉移有15例，肺轉移有6例，骨及多髒器轉移有4例。多因素分析結果錶明LNR、腫瘤類型及分化程度均是影響大腸癌髮生遠處轉移的獨立相關因素（ RR：1．999；CI％：1．101～4．092；P＝0．029）。結論 LNR與大腸癌術後髮生遠處轉移構成獨立相關，可與腫瘤類型、分化程度等作為評估大腸癌術後髮生遠處轉移的參攷指標。
목적：탐토림파결전이도（ LNR）대Ⅲ기대장암환자발생원처전이적예측효과。방법장진행근치성절제수술적55례Ⅲ기대장암환자의거LNR분위2조：저LNR조（LNR＜0．167）화고LNR조（LNR≥0．167）；분석LNR여대장암술후출현원처전이적관계。결과저LNR조（29례，52．7％）중미발생원처전이적환자19례（65．5％），발생원처전이적환자10례（34．5％）；고LNR조（26례，47．3％）중미발생원처전이적환자11례（42．3％），발생원처전이적환자15례（57．7％）。고LNR조교저LNR조적대장암환자경용역발생원처전이；재발생원처전이적환자중，간전이유15례，폐전이유6례，골급다장기전이유4례。다인소분석결과표명LNR、종류류형급분화정도균시영향대장암발생원처전이적독립상관인소（ RR：1．999；CI％：1．101～4．092；P＝0．029）。결론 LNR여대장암술후발생원처전이구성독립상관，가여종류류형、분화정도등작위평고대장암술후발생원처전이적삼고지표。
Objective To study the predictive effect of lymph nodes metastatic ratio( LNR) for distant metastasis in stageⅢcolorectal cancer.Methods 55 patients with stage Ⅲcolorectal cancer were divided into 2 groups based on LNR:low LNR group (LNR<0.167),and high LNR group (LNR≥0.167);the relationship between LNR and distant metastasis in colorectal cancer were analyzed.Results In the low LNR group (29 cases,52.7%),19(65.5%) cases had no distant metastasis,10 (34.5%) cases had distant metastasis.In the high LNR group (26 cases,47.3%),11(42.3%) cases had no distant metasta-sis,15(57.7%)cases had distant metastasis.The high LNR group was more likely to have distant metastasis of colorectal cancer than low LNR group.In patients with distant metastasis,liver metastasis were 15 cases,pulmonary metastasis were 6 cases,bone and multiple organs metastasis were 4 cases.Multi-factor analysis showed that the LNR,tumor type and differentiation were inde-pendent factors correlating to distant metastasis of colorectal cancer(RR:1.999;CI%:1.101~4.092;P=0.029).Conclusion LNR is independently correlated with distant metastasis of colorectal cancer,and serves as an important predicative factor for esti-mating the prognosis of colorectal cancer with tumor type,degree of differentiation.
