CAJ | 학술논문

目的：探讨影响食管癌根治术后患者预后的因素。方法回顾性分析157例食管癌根治术患者的临床病理资料，分析患者的生存情况及其影响因素。结果患者术后1、3、5年的生存率分别为80．89％、43．31％和28．66％。单因素分析表明食管癌根治术后患者预后与肿瘤病变部位、肿瘤长度、分化程度、外侵程度、术后病理分期、淋巴结转移以及术后感染等有关（ P＜0．05）。且随着淋巴结的转移数目、转移度以及转移区域数的增加，患者的死亡率显著上升（ P＜0．01）。多因素分析显示肿瘤长度、分化程度、浸润程度、淋巴结转移及术后感染是影响预后的独立因素。结论食管癌根治术后通过淋巴结转移数目、转移度、转移区域可以更好地评价患者的预后。肿瘤长度、分化、分期、病变部位、浸润程度以及术后感染等是影响患者预后生存的相关因素。
목적：탐토영향식관암근치술후환자예후적인소。방법회고성분석157례식관암근치술환자적림상병리자료，분석환자적생존정황급기영향인소。결과환자술후1、3、5년적생존솔분별위80．89％、43．31％화28．66％。단인소분석표명식관암근치술후환자예후여종류병변부위、종류장도、분화정도、외침정도、술후병리분기、림파결전이이급술후감염등유관（ P＜0．05）。차수착림파결적전이수목、전이도이급전이구역수적증가，환자적사망솔현저상승（ P＜0．01）。다인소분석현시종류장도、분화정도、침윤정도、림파결전이급술후감염시영향예후적독립인소。결론식관암근치술후통과림파결전이수목、전이도、전이구역가이경호지평개환자적예후。종류장도、분화、분기、병변부위、침윤정도이급술후감염등시영향환자예후생존적상관인소。
Objective To explore the influence factors of prognosis of patients with esophageal cancer after radical sur-gery.Methods Clinicopathological data of 157 cases of esophageal cancer were retrospectively analyzed,and survival condition and its influencing factors were analyzed.Results Postoperative 1-,3-,5-year survival rates were 80.89%,43.31% and 28.66%,respectively.Single factor analysis showed that the prognosis of patients with esophageal cancer after radical surgery was related with tumor lesions,tumor length,degree of differentiation,invasion and postoperative pathological staging,lymph node me-tastasis,and postoperative infection and so on(P<0.05).With the increase of number of nodal metastasis,transfer and transfer area,mortality in patients with significantly increased(P<0.01).Multiple factors analysis showed that tumor length,degree of differentiation,infiltration,lymph node metastasis,and postoperative infection were independent prognostic factors.Conclusion Lymph node metastasis number,transfer,transfer area can help evaluate the prognosis of patients with esophageal cancer after rad-ical surgery.Tumor length,degree of differentiation,staging,pathological changes,infiltration and postoperative infection are the related factors influencing the prognosis of patients.