中国中医药现代远程教育
中國中醫藥現代遠程教育
중국중의약현대원정교육
CHINESE MEDICINE MODERN DISTANCE EDUCATION OF CHINA
2015年
6期
61-62
,共2页
逍遥散%氟西汀%冠心病%抑郁症%中西医结合疗法%胸痹%郁证
逍遙散%氟西汀%冠心病%抑鬱癥%中西醫結閤療法%胸痺%鬱證
소요산%불서정%관심병%억욱증%중서의결합요법%흉비%욱증
Xiaoyaos an%Flouxetine%coronary heart disease%depress ion%therapy of integrated medicine%chest pain syndrome%depression syndrome
目的：探讨逍遥散加味联合氟西汀盐酸盐(百忧解)分散片治疗冠心病伴抑郁症的临床疗效。方法将120例冠心病伴抑郁症患者随机分为对照组和治疗组各60例。两组均给予常规方法治疗冠心病(如阿斯匹林、硝酸酯类药物、钙离子拮抗剂、β受体阻滞剂、他汀类药物等），对照组给予氟西汀治疗，治疗组在对照组的基础上加用逍遥散加味治疗。两组均治疗8周后进行疗效临床指标观察。结果在治疗8周后，治疗组的HAMD抑郁量表评分均显著低于对照组，差异有统计学意义(P＜0.05)；治疗8周后，心绞痛症状改善总有效率为90.0%，对照组为76.7%。两组比较，差异有统计学意义(P＜0.05)；不良反应发生率治疗组为6.7%，对照组为16.6%，差异具有统计学意义(P＜0.05)。结论逍遥散加味联合氟西汀治疗冠心病伴抑郁症疗效显著，不良反应少。
目的：探討逍遙散加味聯閤氟西汀鹽痠鹽(百憂解)分散片治療冠心病伴抑鬱癥的臨床療效。方法將120例冠心病伴抑鬱癥患者隨機分為對照組和治療組各60例。兩組均給予常規方法治療冠心病(如阿斯匹林、硝痠酯類藥物、鈣離子拮抗劑、β受體阻滯劑、他汀類藥物等），對照組給予氟西汀治療，治療組在對照組的基礎上加用逍遙散加味治療。兩組均治療8週後進行療效臨床指標觀察。結果在治療8週後，治療組的HAMD抑鬱量錶評分均顯著低于對照組，差異有統計學意義(P＜0.05)；治療8週後，心絞痛癥狀改善總有效率為90.0%，對照組為76.7%。兩組比較，差異有統計學意義(P＜0.05)；不良反應髮生率治療組為6.7%，對照組為16.6%，差異具有統計學意義(P＜0.05)。結論逍遙散加味聯閤氟西汀治療冠心病伴抑鬱癥療效顯著，不良反應少。
목적：탐토소요산가미연합불서정염산염(백우해)분산편치료관심병반억욱증적림상료효。방법장120례관심병반억욱증환자수궤분위대조조화치료조각60례。량조균급여상규방법치료관심병(여아사필림、초산지류약물、개리자길항제、β수체조체제、타정류약물등），대조조급여불서정치료，치료조재대조조적기출상가용소요산가미치료。량조균치료8주후진행료효림상지표관찰。결과재치료8주후，치료조적HAMD억욱량표평분균현저저우대조조，차이유통계학의의(P＜0.05)；치료8주후，심교통증상개선총유효솔위90.0%，대조조위76.7%。량조비교，차이유통계학의의(P＜0.05)；불량반응발생솔치료조위6.7%，대조조위16.6%，차이구유통계학의의(P＜0.05)。결론소요산가미연합불서정치료관심병반억욱증료효현저，불량반응소。
Objective To investigate the efficiency of modified Xiaoyaosan combined with Flouxetine for the treatment of clinical coronary heart disease associated with depression. Methods 120 cases of coronary heart disease associated with depression patients were randomly divided into two groups, 60 cases in each group. Two groups were given conventional treatment of coronary heart disease (such as aspirin, nitrates, calcium antagonists, beta blockers, statins, etc.) . The patients in the control group were treated with Flouxetine; the patients in the observation group were treated with modified Xiaoyaosan combined with Flouxetine. Analyze the clinical efficacy of the two treatments after 8 weeks. Results 8 weeks later, HAMD depression scale score of the treatment group were significantly lower than that of the con-trol group, the difference was statistically significant ( P<0.05) ; the total effective rate of angina symptoms improvement was 90.0%, and was76.7% for the control group, the difference was statistically significant ( P<0.05) . Incidence of adverse reactions in the treatment group was 6.7%, and was 16.6% for the control group, the difference was statistically significant ( P<0.05) . Conclusion Modified Xi-aoyaosan combined with Flouxetine in the treatment of clinical coronary heart disease associated with depression was efficient and had less adverse reaction.
