CAJ | 학술논문

研究讨论遗传性肾病综合征的基因诊断。采用靶序列捕获测序技术对遗传性肾病的病症进行诊断与治疗。遗传性肾病综合征的治疗方案较为复杂，而常规的治疗方案没有明显的效果，如激素和免疫抑制剂。所以，对该类疾病的定义、分子遗传学分类、临床特征以及肾脏病理等相关进展需要进行理解和明确。采用靶序列捕获测序技术，可以一次性对遗传性NS进行检测、诊断和治疗。采用靶序列捕获测序技术对遗传性肾病进行诊断，可以帮助对遗传性肾病综合征的常见分子生物学、临床及病理特征等进行研究，并且为建立遗传性肾病综合征的基因提供诊断依据。
연구토론유전성신병종합정적기인진단。채용파서렬포획측서기술대유전성신병적병증진행진단여치료。유전성신병종합정적치료방안교위복잡，이상규적치료방안몰유명현적효과，여격소화면역억제제。소이，대해류질병적정의、분자유전학분류、림상특정이급신장병리등상관진전수요진행리해화명학。채용파서렬포획측서기술，가이일차성대유전성NS진행검측、진단화치료。채용파서렬포획측서기술대유전성신병진행진단，가이방조대유전성신병종합정적상견분자생물학、림상급병리특정등진행연구，병차위건립유전성신병종합정적기인제공진단의거。
Study and discuss genetic diagnosis of hereditary nephrotic syndrome. Target sequence capture using genetic sequencing technology nephropathy diagnosis and treatment of disease. Regimen hereditary nephrotic syndrome is more complex, while the conventional regimen no significant effects, such as hormone therapy and immunosuppressive hair hair, so the definition of the class of diseases, molecular genetics classification, clinical features, and kidneys pathology and other related developments need to be understood and clear. Target sequence capture using sequencing techniques, can make a one-time NS for genetic testing, diagnosis and treatment. Using molecular biological methods for the diagnosis of hereditary kidney disease, help biology, clinical and pathological features and other common molecular genetic study of nephrotic syndrome, to establish genetic nephrotic syndrome diagnostic thinking.