CAJ | 학술논문

树突状细胞（Dendritic cel s，DC）是具有最强提呈抗原能力的专职抗原提呈细胞，作为机体免疫应答的主要启动者，在免疫应答的诱导中发挥关键作用，可指导原始T细胞向不同的方向分化。DC在抗原进入机体后，通过协调免疫反应与免疫耐受间的平衡，从而在免疫功能方面发挥重要作用。在探索疾病的免疫学机制和相关免疫治疗方案中，DC已经逐渐成为一个重要的研究靶点。基于DC的重要作用，研究DC可以为中医药免疫调节作用机理研究提供新的视角。近年来的研究也表明传统中医药对DC功能状态的调控，是其发挥免疫调节效应的重要环节，现主要就DC的特性和功能及中医药对DC的作用研究进展做一简要综述。
수돌상세포（Dendritic cel s，DC）시구유최강제정항원능력적전직항원제정세포，작위궤체면역응답적주요계동자，재면역응답적유도중발휘관건작용，가지도원시T세포향불동적방향분화。DC재항원진입궤체후，통과협조면역반응여면역내수간적평형，종이재면역공능방면발휘중요작용。재탐색질병적면역학궤제화상관면역치료방안중，DC이경축점성위일개중요적연구파점。기우DC적중요작용，연구DC가이위중의약면역조절작용궤리연구제공신적시각。근년래적연구야표명전통중의약대DC공능상태적조공，시기발휘면역조절효응적중요배절，현주요취DC적특성화공능급중의약대DC적작용연구진전주일간요종술。
Dendritic cell ( DC) is the most professional antigen‐presenting cell, as major initiator of the immune response of the body, plays a key role in the immune response, and guide the T cell differentiation in different directions. DC plays an important role in the balance of the body's immune response and immune tolerance after antigen entering the body. DC has increasingly become an important research target involved in exploring the immunological mechanisms of disease and immune therapy. Based on the importance of dendritic cells, a new view for the research on immune regulation mechanism of traditional Chinese medicine was provided. In recent years, researches showed that traditional Chinese medicine play an important part of the immune regulating effect for regulating dendritic cell's functional state. This review mainly focused on the features and functions of dendritic cells and traditional Chinese medicine research progress on the role of dendritic cells are reviewed.