介入放射学杂志
介入放射學雜誌
개입방사학잡지
JOURNAL OF INTERVENTIONAL RADIOLOGY
2015年
4期
362-368
,共7页
门静脉血栓%病因%临床表现%抗凝治疗%介入治疗
門靜脈血栓%病因%臨床錶現%抗凝治療%介入治療
문정맥혈전%병인%림상표현%항응치료%개입치료
portal vein thrombosis%etiology%clinical manifestation%anticoagulation therapy%interventional treatment
随着影像诊断技术的进步,曾被认为是罕见病的门静脉系统血栓的确诊率迅速上升。全身因素(包括各种促血栓形成的危险因素)以及局部因素(包括肝硬化、腹腔创伤及感染、恶性肿瘤等)均可导致门静脉血栓形成。目前依据临床症状出现时间的长短以及是否存在门脉海绵样变将门静脉系统血栓分为急性和慢性两类,这两类门静脉系统血栓分别具有不同的临床表现及治疗原则。急性血栓的治疗原则为复通闭塞的门静脉,降低血栓进入肠系膜上静脉的危险性;慢性血栓则为治疗和预防门脉高压后产生的并发症。门静脉系统血栓的介入治疗在血管再通、减轻门脉高压引起的并发症以及恢复阻塞静脉血流方面起到很大作用。本文将就门静脉系统血栓从病因到治疗的最新进展做一综述。
隨著影像診斷技術的進步,曾被認為是罕見病的門靜脈繫統血栓的確診率迅速上升。全身因素(包括各種促血栓形成的危險因素)以及跼部因素(包括肝硬化、腹腔創傷及感染、噁性腫瘤等)均可導緻門靜脈血栓形成。目前依據臨床癥狀齣現時間的長短以及是否存在門脈海綿樣變將門靜脈繫統血栓分為急性和慢性兩類,這兩類門靜脈繫統血栓分彆具有不同的臨床錶現及治療原則。急性血栓的治療原則為複通閉塞的門靜脈,降低血栓進入腸繫膜上靜脈的危險性;慢性血栓則為治療和預防門脈高壓後產生的併髮癥。門靜脈繫統血栓的介入治療在血管再通、減輕門脈高壓引起的併髮癥以及恢複阻塞靜脈血流方麵起到很大作用。本文將就門靜脈繫統血栓從病因到治療的最新進展做一綜述。
수착영상진단기술적진보,증피인위시한견병적문정맥계통혈전적학진솔신속상승。전신인소(포괄각충촉혈전형성적위험인소)이급국부인소(포괄간경화、복강창상급감염、악성종류등)균가도치문정맥혈전형성。목전의거림상증상출현시간적장단이급시부존재문맥해면양변장문정맥계통혈전분위급성화만성량류,저량류문정맥계통혈전분별구유불동적림상표현급치료원칙。급성혈전적치료원칙위복통폐새적문정맥,강저혈전진입장계막상정맥적위험성;만성혈전칙위치료화예방문맥고압후산생적병발증。문정맥계통혈전적개입치료재혈관재통、감경문맥고압인기적병발증이급회복조새정맥혈류방면기도흔대작용。본문장취문정맥계통혈전종병인도치료적최신진전주일종술。
With the progress of imaging techniques, the diagnosis rate for portal vein thrombosis (PVT), that is used to be considered as a rare disease, has been rapidly increasing. PVT can be caused by systemic reasons such as various thrombophilic risk factors as well as a lot of local reasons such as cirrhosis, abdominal trauma and infection, malignant tumor, etc. At present, PVT is classified into acute and chronic entities based on the duration of clinical symptoms as well as on the presence or absence of portal cavernous transformation. The clinical manifestations and the treatment principles of the acute and chronic PVT are quite different. For acute PVT, the principle of treatment is to reopen the obstructed portal vein and to prevent the thrombus from entering into the superior mesenteric vein, while for chronic PVT the principle of treatment is focused on the management of the complications due to portal hypertension. The interventional management of portal thrombus plays an important role in reopening portal vein, reducing complications caused by portal hypertension, and restoring portal blood flow, etc. This paper aims to make a comprehensive review about the etiology and management of portal vein thrombosis.