CAJ | 학술논문

采用石膏固定建立后肢制动模型，用空气隔绝法记录大鼠单一肌梭的电生理活动，用振动仪给制动＋振动组比目鱼肌施加高频振动，7d后观察大鼠制动侧比目鱼肌肌梭的电生理活动变化。比目鱼肌的湿重与非制动侧相比降低了15.33％±4.76％（ P＜0.05）；有自发放电的肌梭数量减少（ P＜0.05）；静息放电频率降低（ P＜0.05）。制动期间施加高频振动组，比目鱼肌湿重减少的程度明显降低（ P＜0.05）；自发放电的肌梭数量、肌梭的放电频率明显高于制动组（ P＜0.05）。制动期间的肌肉振动对制动所致肌梭电生理活动特性的改变有明显的对抗作用。
채용석고고정건립후지제동모형，용공기격절법기록대서단일기사적전생리활동，용진동의급제동＋진동조비목어기시가고빈진동，7d후관찰대서제동측비목어기기사적전생리활동변화。비목어기적습중여비제동측상비강저료15.33％±4.76％（ P＜0.05）；유자발방전적기사수량감소（ P＜0.05）；정식방전빈솔강저（ P＜0.05）。제동기간시가고빈진동조，비목어기습중감소적정도명현강저（ P＜0.05）；자발방전적기사수량、기사적방전빈솔명현고우제동조（ P＜0.05）。제동기간적기육진동대제동소치기사전생리활동특성적개변유명현적대항작용。
To investigate the effects of muscle vibration on the electrophysiological activity of isolated muscle spindles in rat following hind limb immobilization , the limb immobilization model in rat was induced with plaster cast .The electrophysiological activities of the isolated muscle spindles were recorded by air-gap technique .The muscle vibration was applied to the immobilized soleus muscle with a home-made vibrator.Results showed that after 7 days′immobilization, significant reduction in muscle mass (15.33%±4.76%com-pared with the contralateral non-immobilized muscle ) was found ( P<0.05 ); the numbers of muscle spindles with spontaneous dis-charges decreased ( P<0.05 ) and the spontaneous impulses decreased ( P<0.05 ) .With sinusodial vibration during 7 days of immobi-lization, the loss of muscle mass was significantly attenuated and no significant changes in electrophysiological activities of isolated mus -cle spindles occurred .It indicated that the muscle vibration during the immobilization could guard against the changes of muscle spin -dles′electrophysiological activity induced by hind limb immobilization .