CAJ | 학술논문

以桑叶为原料，对桑叶提取物泡腾片的制备工艺及其体外抗氧化活性进行了研究．采取超声波辅助乙醇萃取法提取桑叶功能性成分，添加0.15 g／m L麦芽糊精，真空冷冻干燥9 h后粉碎过180μm筛，得到桑叶提取物冻干粉．桑叶提取物泡腾片宜采用湿法制粒，配方为桑叶提取物冻干粉5％，柠檬酸12％，碳酸氢钠7.5％，甘露醇7％，葡萄糖30％，蔗糖38.5％．桑叶提取物泡腾片对羟自由基，DPPH自由基和超氧阴离子自由基的半数清除率（IC50）分别为49.78，77.12和94.98 m g／m L ．
이상협위원료，대상협제취물포등편적제비공예급기체외항양화활성진행료연구．채취초성파보조을순췌취법제취상협공능성성분，첨가0.15 g／m L맥아호정，진공냉동간조9 h후분쇄과180μm사，득도상협제취물동간분．상협제취물포등편의채용습법제립，배방위상협제취물동간분5％，저몽산12％，탄산경납7.5％，감로순7％，포도당30％，자당38.5％．상협제취물포등편대간자유기，DPPH자유기화초양음리자자유기적반수청제솔（IC50）분별위49.78，77.12화94.98 m g／m L ．
To study the preparation technology and antioxidant activity in vitro of mulberry leaves extract efferves‐cent tablets ,research methods of extract and vacuum freeze‐drying mulberry leaves bioactive substances have been explored according to the sensory evaluation and tabletting effect by means of choosing the appropriate effervescent tablets formulation .ultrasonic‐assisted ethanol has been used to extract the functional components of mulberry leaves .The 180μm sieve freeze‐drying mulberry power has been obtained by adding 0.15 g/mL maltodextrin .The tablets could be prepared very well by the wet granulation process and the optimal formulais determined as fol‐lows:5% of mulberry leaves extract ,12% of citric acid ,7 5.% of sodium bicarbonate ,7% of mannitol ,30% of glucose ,38 5.% of sugar .The IC50 values of · OH ,DPPH · and O2 - · of mulberry leaves extract effervescent tablets are 49 7.8 ,77 1.2 and 94 9.8 mg/mL respectively .