中国康复理论与实践
中國康複理論與實踐
중국강복이론여실천
CHINESE JOURNAL OF REHABILITATION THEORY & PRACTICE
2015年
4期
432-435
,共4页
吴建龙%乔建勇%段庆华
吳建龍%喬建勇%段慶華
오건룡%교건용%단경화
侵袭性垂体瘤%肿瘤坏死因子-α%白细胞介素-6
侵襲性垂體瘤%腫瘤壞死因子-α%白細胞介素-6
침습성수체류%종류배사인자-α%백세포개소-6
invasive pituitary adenoma%tumor necrosis factor-α%interleukin-6
目的:研究肿瘤坏死因子-α(TNF-α)和白细胞介素-6(IL-6)在侵袭性垂体瘤(IPA)中的表达。方法采用免疫组织化学方法(SP法)检测40例IPA和40例非侵袭性垂体瘤(NIPA)组织中TNF-α和IL-6的表达。结果 TNF-α、IL-6在IPA组织中的表达均高于NIPA (P<0.05)。结论 TNF-α、IL-6可能在IPA的发生、发展过程发挥作用。
目的:研究腫瘤壞死因子-α(TNF-α)和白細胞介素-6(IL-6)在侵襲性垂體瘤(IPA)中的錶達。方法採用免疫組織化學方法(SP法)檢測40例IPA和40例非侵襲性垂體瘤(NIPA)組織中TNF-α和IL-6的錶達。結果 TNF-α、IL-6在IPA組織中的錶達均高于NIPA (P<0.05)。結論 TNF-α、IL-6可能在IPA的髮生、髮展過程髮揮作用。
목적:연구종류배사인자-α(TNF-α)화백세포개소-6(IL-6)재침습성수체류(IPA)중적표체。방법채용면역조직화학방법(SP법)검측40례IPA화40례비침습성수체류(NIPA)조직중TNF-α화IL-6적표체。결과 TNF-α、IL-6재IPA조직중적표체균고우NIPA (P<0.05)。결론 TNF-α、IL-6가능재IPA적발생、발전과정발휘작용。
Objective To study the tumor necrosis factor-α(TNF-α) and interleukin-6 (IL-6) expressed in invasive pituitary adenomas (IPA). Methods The expression of TNF-α and IL-6 were observed with immunohistochemstry (SP approach) in tissue from 40 cases of non-invasive pituitary adenomas (NIPA) and 40 cases of IPA. Results The expression of both TNF-αand IL-6 was significantly increased in the IPA tissues compared with those of NIPA (P<0.05). Conclusion TNF-αand IL-6 may play a role in the occurrence and development of IPA.