CAJ | 학술논문

目的：评价局部浸润镇痛在初次单侧全膝关节置换术（total knee replacement，TKR）多模式镇痛中的镇痛效果及安全性。方法：将22例骨关节炎初次单侧TKR手术的患者随机分为局部浸润镇痛组（ A组）与无局部浸润镇痛组（ B组），每组11例。比较患者术后膝关节静息疼痛视觉模拟评分（ visual analog score ，VAS）、膝关节活动度及并发症。结果：A组术后各时点的静息VAS评分均低于B组，术后8、12、24、48 h A组静息痛VAS评分显著小于B组，术后24、48、72 h A组关节活动度较B组明显增加。镇痛相关不良反应发生率差异无统计学意义。结论：以局部浸润镇痛为主的多模式镇痛在初次单侧TKR术后有较好的镇痛效果，有助于减轻术后早期疼痛，且没有明显的不良反应。
목적：평개국부침윤진통재초차단측전슬관절치환술（total knee replacement，TKR）다모식진통중적진통효과급안전성。방법：장22례골관절염초차단측TKR수술적환자수궤분위국부침윤진통조（ A조）여무국부침윤진통조（ B조），매조11례。비교환자술후슬관절정식동통시각모의평분（ visual analog score ，VAS）、슬관절활동도급병발증。결과：A조술후각시점적정식VAS평분균저우B조，술후8、12、24、48 h A조정식통VAS평분현저소우B조，술후24、48、72 h A조관절활동도교B조명현증가。진통상관불량반응발생솔차이무통계학의의。결론：이국부침윤진통위주적다모식진통재초차단측TKR술후유교호적진통효과，유조우감경술후조기동통，차몰유명현적불량반응。
Objective:To evaluate the analgesic efficacy and safety of local infiltration analgesia in a multimodal analgesia protocol for primary unilateral total knee replacement(TKR).Methods:Twenty-two patients with osteoarthritis,scheduled to undergo primary unilateral TKR,were prospectively assigned to two groups(n=11 for each group).Group A were managed with local infiltration analgesia,and group B with non-local infiltration analgesia.The two groups were evaluated regarding the resting pain by visual analog score (VAS),range of motion and complications after operation.Results: Group A had lower VAS scores and post-operative VAS scoring at rest at 8,12,24 and 48 h,respectively,and better range of motion after operation as compared with group B.The adverse events associated with analgesia were not significant for the two groups.Conclusion:This multimodal analgesia protocol may produce better infiltration analgesic effects and early pain control for patients following TKR without significant adverse effects .