CAJ | 학술논문

目的：探讨应用去氧肾上腺素后脉搏压变异度（PPV）和每搏量变异度（SVV）的相关性。方法选择肝胆外科择期肝脏切除手术患者20例，全麻诱导后循环稳定时，记录心率（HR）、动脉收缩压（SAP）、心输出量（CO）、心输出量指数（CI）、每搏量（SV）、每搏量指数（SVI）、PPV和SVV ，改变去氧肾上腺素泵入速度使SAP分别提高10%<ΔSAP≤20%、20%<ΔSAP≤30%和30%<ΔSAP≤40%并记录上述参数，对各个压力阶段的PPV和SVV进行相关性分析。结果去氧肾上腺素降低PPV和SVV值，各压力水平的PPV和SVV的数值具有高度相关性：T1，r=0.935，P<0.01；T2，r=0.947，P<0.01；T3，r=0.971，P<0.01；T4，r=0.973，P<0.01。结论虽然去氧肾上腺素高估了容量状态，但是脉搏压变异度（PPV）和每搏量变异度（SVV）在应用去氧肾上腺素后依然具有高度相关性。
목적：탐토응용거양신상선소후맥박압변이도（PPV）화매박량변이도（SVV）적상관성。방법선택간담외과택기간장절제수술환자20례，전마유도후순배은정시，기록심솔（HR）、동맥수축압（SAP）、심수출량（CO）、심수출량지수（CI）、매박량（SV）、매박량지수（SVI）、PPV화SVV ，개변거양신상선소빙입속도사SAP분별제고10%<ΔSAP≤20%、20%<ΔSAP≤30%화30%<ΔSAP≤40%병기록상술삼수，대각개압력계단적PPV화SVV진행상관성분석。결과거양신상선소강저PPV화SVV치，각압력수평적PPV화SVV적수치구유고도상관성：T1，r=0.935，P<0.01；T2，r=0.947，P<0.01；T3，r=0.971，P<0.01；T4，r=0.973，P<0.01。결론수연거양신상선소고고료용량상태，단시맥박압변이도（PPV）화매박량변이도（SVV）재응용거양신상선소후의연구유고도상관성。
Objective To evaluate the correlation between the pulse pressure variation(PPV)and stroke volume variation(SVV)after using phenylephrine. Methods Twenty patients underwent liver partial resection with ASA I~II were selected to this study. After anesthesia induction and the circulation state became stable, HR, SAP, CO, CI, SV, SVI, PPV and SVV were recorded(T1). Changing the phenylephrine injection speed to make the SAP increase:10%<ΔSAP≤20%(T2), 20%<ΔSAP≤30%(T3), 30%<ΔSAP≤40%(T4)and calculate the correlation coefficient(r)of every SAP level. Results Phenylephrine decreased the PPV and SVV value,there was a significant correlation between PPV and SVV at four SAP levels according to the linear regression analysis:T1, r=0.935, P<0.01;T2, r=0.947, P<0.01;T3, r=0.971, P<0.01;T4, r=0.973, P<0.01. Conclusion Phenylephrine can mis-interpret and overestimate patients’volume state, but PPV and SVV are well correlated when using it.