CAJ | 학술논문

目的：研究高血压患者昼夜血压节律与无症状性心肌缺血的相关性。方法选取2012年3月—2014年3月就诊的164例原发性高血压患者为研究对象，采用问卷调查和临床检查的方式收集患者的信息，通过单因素分析和Logistic回归分析患者昼夜血压节律与无症状性心肌缺血的关系。结果在调整了年龄、文化水平、婚姻状况、吸烟状况、饮酒状况、体质指数（ BMI）、收缩压水平、舒张压水平以及血糖水平等因素后，二元Logistic回归分析结果显示相比于杓型的患者，昼夜节律为反杓型、非杓型和超杓型的患者患有心肌缺血的风险都明显升高，其OR值和95％CI分别为1．38（1．15～1．61）、1．24（1．09～1．39）和1．57（1．36～1．78）。结论对于原发性高血压病的患者，预防并发心肌缺血的关键除控制血压外，还应重视血压昼夜节律是否异常。
목적：연구고혈압환자주야혈압절률여무증상성심기결혈적상관성。방법선취2012년3월—2014년3월취진적164례원발성고혈압환자위연구대상，채용문권조사화림상검사적방식수집환자적신식，통과단인소분석화Logistic회귀분석환자주야혈압절률여무증상성심기결혈적관계。결과재조정료년령、문화수평、혼인상황、흡연상황、음주상황、체질지수（ BMI）、수축압수평、서장압수평이급혈당수평등인소후，이원Logistic회귀분석결과현시상비우표형적환자，주야절률위반표형、비표형화초표형적환자환유심기결혈적풍험도명현승고，기OR치화95％CI분별위1．38（1．15～1．61）、1．24（1．09～1．39）화1．57（1．36～1．78）。결론대우원발성고혈압병적환자，예방병발심기결혈적관건제공제혈압외，환응중시혈압주야절률시부이상。
Objective To analyze the relationship between circadian rhythm of blood pressure and silent myocardial ischemia in essential hypertension patients.Methods A total 420 essential hypertension patients from March 2012 to March 2014 in our hospital were recrui-ted in the study.Quality-of-life questionnaire and clinical examination were used to collect the information of patients.Univariate analysis and multiple linear regression analysis were used to investigate the relationship between circadian rhythm of blood pressure and silent myo-cardial ischemia in hypertensive patients.Results After adjusting for the confounding effects of age,educational level,marital status, smoking status,alcohol consumption status,BMI,systolic blood pressure,diastolic blood pressure and blood sugar levels,the logistic re-gression results showed that patients with reverse-dippers,non-dippers and over-dippers blood pressure rhythm had greater risk for hav-ing silent myocardial ischemia compared with those with dippers blood pressure rhythm,and the OR and 95%CI were 1.38(1.15~1.61),1.24(1.09~1.39) and 1.57(1.36~1.78),respectively.Conclusions For patients with essential hypertension,the key to prevention of myocardial ischemia was examine the blood pressure rhythm abnormalities in addition to the concurrent control blood pressure.