天津医药
天津醫藥
천진의약
TIANJIN MEDICAL JOURNAL
2015年
4期
443-445
,共3页
动脉粥样硬化%代谢综合征X%肠杆菌科%心血管疾病%胆固醇%氧化三甲胺
動脈粥樣硬化%代謝綜閤徵X%腸桿菌科%心血管疾病%膽固醇%氧化三甲胺
동맥죽양경화%대사종합정X%장간균과%심혈관질병%담고순%양화삼갑알
atherosclerosis%metabolic syndrome X%enterobacteriaceae%cardiovascular diseases%cholesterol%trimetlyl-amine oxide
最新研究表明,肠道菌群与代谢综合征关系密切,与其重要的靶器官心血管系统关系尤为显著。肠道菌群对胆固醇、胆汁酸的代谢直接影响血中胆固醇的水平,同时胆固醇的水平又是动脉粥样硬化形成的关键环节。本文主要对肠道菌群依赖性代谢产物氧化三甲胺(trimetlylamine oxide,TMAO)与心血管疾病发病的根源动脉粥样硬化的关系进行综述。
最新研究錶明,腸道菌群與代謝綜閤徵關繫密切,與其重要的靶器官心血管繫統關繫尤為顯著。腸道菌群對膽固醇、膽汁痠的代謝直接影響血中膽固醇的水平,同時膽固醇的水平又是動脈粥樣硬化形成的關鍵環節。本文主要對腸道菌群依賴性代謝產物氧化三甲胺(trimetlylamine oxide,TMAO)與心血管疾病髮病的根源動脈粥樣硬化的關繫進行綜述。
최신연구표명,장도균군여대사종합정관계밀절,여기중요적파기관심혈관계통관계우위현저。장도균군대담고순、담즙산적대사직접영향혈중담고순적수평,동시담고순적수평우시동맥죽양경화형성적관건배절。본문주요대장도균군의뢰성대사산물양화삼갑알(trimetlylamine oxide,TMAO)여심혈관질병발병적근원동맥죽양경화적관계진행종술。
Recent researches revealed that intestinal flora contribute to the development of metabolic syndrome, espe?cially to the disorder of their targeted cardiovascular system. Blood cholesterol level is affected by the metabolism of intesti?nal flora in cholesterol and bile acid. At the same time, the blood cholesterol level is the key player in development of athero?sclerosis. This review mainly discussed the relationship between the intestinal flora dependent metabolite trimethylamine ox?ide (Trimetlylamine oxide, TMAO) and atherosclerosis.