CAJ | 학술논문

目的：探讨老年恶性肿瘤并发医院获得性肺炎（hospital acquired pneumonia,HAP）的临床特点及病原学分析。方法回顾性分析157例老年晚期恶性肿瘤并发HAP的病例资料。结果中低热占88.5%，高热仅占11.5%；有呼吸系统症状者占76.2%，无呼吸系统症状而仅表现为精神萎靡者占23.8％；白细胞总数明显增高的仅占47.8％；65.6％的患者中性粒细胞比例明显增高；肺部听诊96.2％存在干、湿啰音。痰培养阳性率仅43.41％，其中革兰阴性菌占66.29％，革兰阳性菌占23.60％，真菌占10.11％。结论老年恶性肿瘤并发HAP发病率高，临床表现不同于其他患者，病原菌以革兰阴性菌为主。
목적：탐토노년악성종류병발의원획득성폐염（hospital acquired pneumonia,HAP）적림상특점급병원학분석。방법회고성분석157례노년만기악성종류병발HAP적병례자료。결과중저열점88.5%，고열부점11.5%；유호흡계통증상자점76.2%，무호흡계통증상이부표현위정신위미자점23.8％；백세포총수명현증고적부점47.8％；65.6％적환자중성립세포비례명현증고；폐부은진96.2％존재간、습라음。담배양양성솔부43.41％，기중혁란음성균점66.29％，혁란양성균점23.60％，진균점10.11％。결론노년악성종류병발HAP발병솔고，림상표현불동우기타환자，병원균이혁란음성균위주。
Objective To investigate the clinical characteristics and pathogens in elderly patients with malignant tu-mor complicated with hospital acquired pneumonia. Methods The clinical data of 157 cases of elderly patients with ma-lignant tumor complicated with hospital acquired pneumonia were retrospectively analyzed. Results Low to moderate fe-ver occurred in 88.5%of patients, only 11.5%patients had high fever. 76.2%patients had respiratory symptoms (), only 23.8%patients had no respiratory symptoms but had lathergy . Only 47.8%patients had leukocytosis , the proportion of neutrophils was significantly increased in 65.6%of patients . Rales or rhonchi were detected in 96.2%patients during lung auscultation. Sputum culture was positive in 43.41% of patients, among which 66.29% were Gram negative bacteria, 23.6%were Gram positive bacteria, 10.11%were fungi. Conclusion The incidence HAP is high in elderly patients with malignant tumor . Clinical manifestations are different from those patients without malignant tumors, and the majority of them are infected with Gram negative bacteria.