CAJ | 학술논문

目的：探讨NICU中新生儿重度高胆红素血症换血治疗的应用及效果。方法选取2013年1月-2014年3月该院新生儿监护病房收治的重度高胆红素血症新生儿57例，采用外周动静脉同步换血方式进行治疗，换血中密切监测患者生命体征、血糖等指标变化，并在结束治疗后进行血常规、血生化等检查比较。结果所有患儿经换血治疗后血清总胆红素和间接胆红素等均显著下降，6例患儿出现贫血，22例患儿出现血小板减少，49例患儿出现高血糖症，无血钙、血钠及血钾异常改变。结论在新生儿重度高胆红素血症临床治疗过程中，采用外周动静脉同步换血治疗可有效降低血清胆红素，同时对患儿不良反应少，值得在临床上进行推广和应用。
목적：탐토NICU중신생인중도고담홍소혈증환혈치료적응용급효과。방법선취2013년1월-2014년3월해원신생인감호병방수치적중도고담홍소혈증신생인57례，채용외주동정맥동보환혈방식진행치료，환혈중밀절감측환자생명체정、혈당등지표변화，병재결속치료후진행혈상규、혈생화등검사비교。결과소유환인경환혈치료후혈청총담홍소화간접담홍소등균현저하강，6례환인출현빈혈，22례환인출현혈소판감소，49례환인출현고혈당증，무혈개、혈납급혈갑이상개변。결론재신생인중도고담홍소혈증림상치료과정중，채용외주동정맥동보환혈치료가유효강저혈청담홍소，동시대환인불량반응소，치득재림상상진행추엄화응용。
Objective To investigate the application and effect of NICU in neonates with severe hyperbilirubinemia exchange trans-fusion therapy. Methods From 2013 January to 2014 March in our hospital neonatal intensive care ward in neonates with severe hyperbilirubinemia in 57 cases, the peripheral arteriovenous synchronous exchange transfusion for exchange transfusion, closely monitoring changes in patients with vital signs, blood glucose and other indicators, and at the end of treatment of blood routine, biochemical examination. Results All patients after exchange transfusion on serum total bilirubin and indirect bilirubin decreased significantly, 6 cases of anemia, 22 cases of thrombocytopenia, 49 cases of hyperglycemia, abnormal changes without serum calci-um, sodium and serum potassium. Conclusion In severe neonatal hyperbilirubinemia in clinical treatment process, using the pe-ripheral arteriovenous synchronous exchange transfusion treatment can effectively reduce serum bilirubin, and with less side effect, it is worth of promotion and application in clinical practice.