广西医学
廣西醫學
엄서의학
GUANGXI MEDICAL JOURNAL
2015年
2期
160-162
,共3页
陈兰%吕小平%詹灵凌%罗虹%梁远%唐国都
陳蘭%呂小平%詹靈凌%囉虹%樑遠%唐國都
진란%려소평%첨령릉%라홍%량원%당국도
肠易激综合征%食物不耐受特异性IgG%饮食治疗%非变应性食物过敏症
腸易激綜閤徵%食物不耐受特異性IgG%飲食治療%非變應性食物過敏癥
장역격종합정%식물불내수특이성IgG%음식치료%비변응성식물과민증
Irritable bowel syndrome%Specific IgG of food intolerance%Diet therapy%Non-allergic food allergy
目的：探讨食物不耐受特异性IgG抗体与肠易激综合征（ IBS）的关系。方法对128例IBS患者和80例健康体检者，应用酶联免疫吸附法半定量检测血清中14种食物不耐受特异性lgG抗体水平并分为0、＋1、＋2和＋3级；根据检测结果剔除相应食物治疗8周，采用调查表评分系统对IBS患者的症状进行评分以评价疗效。结果128例IBS患者中，至少有1种食物不耐受特异性IgG抗体阳性112例，阳性率为87．5％，明显高于对照组的9．3％（ P＜0．05）。 IBS患者食物不耐受特异性IgG阳性率以蟹（84．4％）和虾（75．0％）较高。128例IBS患者中IgG抗体阳性＋2以上的患者82例，经剔除相应食物治疗8周后，临床症状明显改善56例（68．3％），症状有所改善16例（19．5％），无效10例（12．2％），总有效率为87．8％（72／82）。结论根据IBS患者血清中食物不耐受特异性IgG水平，剔除相应食物，能有效地改善IBS的临床症状。
目的：探討食物不耐受特異性IgG抗體與腸易激綜閤徵（ IBS）的關繫。方法對128例IBS患者和80例健康體檢者，應用酶聯免疫吸附法半定量檢測血清中14種食物不耐受特異性lgG抗體水平併分為0、＋1、＋2和＋3級；根據檢測結果剔除相應食物治療8週，採用調查錶評分繫統對IBS患者的癥狀進行評分以評價療效。結果128例IBS患者中，至少有1種食物不耐受特異性IgG抗體暘性112例，暘性率為87．5％，明顯高于對照組的9．3％（ P＜0．05）。 IBS患者食物不耐受特異性IgG暘性率以蟹（84．4％）和蝦（75．0％）較高。128例IBS患者中IgG抗體暘性＋2以上的患者82例，經剔除相應食物治療8週後，臨床癥狀明顯改善56例（68．3％），癥狀有所改善16例（19．5％），無效10例（12．2％），總有效率為87．8％（72／82）。結論根據IBS患者血清中食物不耐受特異性IgG水平，剔除相應食物，能有效地改善IBS的臨床癥狀。
목적：탐토식물불내수특이성IgG항체여장역격종합정（ IBS）적관계。방법대128례IBS환자화80례건강체검자，응용매련면역흡부법반정량검측혈청중14충식물불내수특이성lgG항체수평병분위0、＋1、＋2화＋3급；근거검측결과척제상응식물치료8주，채용조사표평분계통대IBS환자적증상진행평분이평개료효。결과128례IBS환자중，지소유1충식물불내수특이성IgG항체양성112례，양성솔위87．5％，명현고우대조조적9．3％（ P＜0．05）。 IBS환자식물불내수특이성IgG양성솔이해（84．4％）화하（75．0％）교고。128례IBS환자중IgG항체양성＋2이상적환자82례，경척제상응식물치료8주후，림상증상명현개선56례（68．3％），증상유소개선16례（19．5％），무효10례（12．2％），총유효솔위87．8％（72／82）。결론근거IBS환자혈청중식물불내수특이성IgG수평，척제상응식물，능유효지개선IBS적림상증상。
Objective To explore the relationship between specific IgG antibody of food intolerance and irritable bowel syndrome ( IBS) .Methods The levels of 14 serum specific lgG antibodies of food intolerance were detected by semi-quantitative enzyme-linked immunosorbent assay among 128 patients with IBS and 80 healthy controls,which were classified into grade 0,grade +1,grade +2 and grade +3.The patients were treated for 8 weeks following eliminating the corresponding foods according to the result of the detection .And then a questionnaire scoring system was applied to assessing the effects on the patients according to the symptoms of patients with IBS . Results Among 128 patients with IBS,there were 112 with one or more specific lgG antibodies of food intolerance ,with a positive rate of 87.5%which was significantly higher than that(9.3%) of control group(P<0.05).The most common intolerant foods were crab(the positive rate of 84.4%)and shrimp (the positive rate of 75.0%) in patients with IBS.Eighty-two of 128 IBS patients,with positive IgG antibody of grade+2 or higher,received a diet therapy of eliminating the corresponding food for 8 weeks.Of these 82 cases,56(68.3%)improved significantly, 16(19.5%) improved,10(12.2%) ineffective,the overall effective rate was 87.8%(72/82).Conclusion The measurement of eliminating the corresponding food according to the level of specific IgG antibody of food intolerance might contribute to improving the clinical symptoms of IBS .
