CAJ | 학술논문

目的：探讨阿立哌唑与利培酮治疗女性精神分裂症的临床效果。方法选择该院2012年1月—2014年1月间收治的100例女性精神分裂症患者进行临床研究，随机将患者分为阿立哌唑组和利培酮组，对比分析两组患者临床治疗效果。结果两组观察对象临床治疗前PANSS精神病理、阴性症状、阳性症状和总分对比差异无统计学意义（P>0.05），临床治疗2周、治疗4周和治疗8周后PANSS精神病理、阴性症状、阳性症状和总分对比差异具有统计学意义（P<0.05）。两组女性精神分裂症患者临床治疗的总有效率和不良反应发生率对比差异具有统计学意义（P<0.05）。结论该次医学研究结果证实，阿立哌唑用于女性精神分裂症的临床治疗，具有更高的有效率和安全性，因而临床推广和应用价值更高。
목적：탐토아립고서여리배동치료녀성정신분렬증적림상효과。방법선택해원2012년1월—2014년1월간수치적100례녀성정신분렬증환자진행림상연구，수궤장환자분위아립고서조화리배동조，대비분석량조환자림상치료효과。결과량조관찰대상림상치료전PANSS정신병리、음성증상、양성증상화총분대비차이무통계학의의（P>0.05），림상치료2주、치료4주화치료8주후PANSS정신병리、음성증상、양성증상화총분대비차이구유통계학의의（P<0.05）。량조녀성정신분렬증환자림상치료적총유효솔화불량반응발생솔대비차이구유통계학의의（P<0.05）。결론해차의학연구결과증실，아립고서용우녀성정신분렬증적림상치료，구유경고적유효솔화안전성，인이림상추엄화응용개치경고。
Objective To investigate the clinical effect of aripiprazole and risperidone in the treatment of female schizophrenia. Methods 100 cases of female spirit admitted in our hospital in 2012 January to 2014 January between the schizophrenia patients for clinical research,The patients were randomly divided into aripiprazole group and risperidone group, compared two groups of patients with clinical curative effect. Results In the two groups before treatment PANSS clinical psychopathology, negative symptoms, positive symptoms and score of contrast was no significant statistical difference (P>0.05), the clinical treatment for 2 weeks, 4 weeks of treatment and 8 weeks after the treatment, PANSS psychopathology, negative symptoms, positive symptoms and total score compared with the statistically significant difference (P<0.05). Two groups of female patients with schizophrenia clinical total effective rate and the incidence of adverse reactions compared with significant statistical difference (P<0.05) Conclusion The results suggest that aripiprazole for the clinical treatment of female schizophrenia has higher efficient and safety, then we should take measure for clinical popularization and application.