CAJ | 학술논문

我国男性前列腺癌的发病率和死亡率均呈逐年上升趋势,本文对前列腺癌的当前热点研究进行概述和前景展望.前列腺特异抗原(PSA)人群筛查的价值仍存争议,在高危人群进行血清PSA筛查可以尽早发现可能存在的前列腺癌.前列腺穿刺活检包括经直肠途径和经会阴途径,两种穿刺方式各有优劣.睾酮水平与前列腺癌的预后有明显相关性,睾酮水平变化的监测有助于合理调整治疗方案.前列腺癌根治性手术的主要并发症是尿失禁和勃起功能障碍,三维腹腔镜和机器人辅助腹腔镜技术在前列腺癌根治术中优势明显;近距离放射治疗是根治性治疗的另一种选择,年龄限制明显放宽,勃起功能障碍及尿失禁的发生率较低,疗效可靠.目前前列腺癌诊疗新技术还包括了如MRI动态增强扫描、18F-氟乙基胆碱PET/CT、超声微泡造影技术、前列腺癌免疫治疗等.
아국남성전렬선암적발병솔화사망솔균정축년상승추세,본문대전렬선암적당전열점연구진행개술화전경전망.전렬선특이항원(PSA)인군사사적개치잉존쟁의,재고위인군진행혈청PSA사사가이진조발현가능존재적전렬선암.전렬선천자활검포괄경직장도경화경회음도경,량충천자방식각유우렬.고동수평여전렬선암적예후유명현상관성,고동수평변화적감측유조우합리조정치료방안.전렬선암근치성수술적주요병발증시뇨실금화발기공능장애,삼유복강경화궤기인보조복강경기술재전렬선암근치술중우세명현;근거리방사치료시근치성치료적령일충선택,년령한제명현방관,발기공능장애급뇨실금적발생솔교저,료효가고.목전전렬선암진료신기술환포괄료여MRI동태증강소묘、18F-불을기담감PET/CT、초성미포조영기술、전렬선암면역치료등.
The incidence and mortality of prostate cancer in China are increasing year by year.The review is focused on current hot prospects of prostate cancer.The value of serum prostate specific antigen (PSA) screening is still controversial,and PSA screening in high-risk groups is recommended for early diagnosis of prostate cancer.Prostate biopsy including transrectal approach and perineal approach,and two methods have both advantages and disadvantages.There is significant correlation between testosterone levels and the prognosis of prostate cancer,and the monitoring of testosterone level contributes to the treatment.The main complications of radical resection of prostate cancer is urinary incontinence and erectile dysfunction,three-dimensional laparoscopic and robot assisted laparoscopic techniques have obvious advantages in radical operation.Brachytherapy is another option for radical treatment,with relaxed age limit,low incidence of erectile dysfunction,urinary incontinence and reliable curative effect.The diagnosis and treatment of new technologies include such as MRI dynamic enhancement scan,18F-fluoroethyl PET/CT,ultrasound contrast technology,prostate cancer immunotherapy,et al.