脾切除贲门周围血管离断术对患者肝功能及肝脏血流动力学的影响
비절제분문주위혈관리단술대환자간공능급간장혈류동역학적영향
The function and heamodynamics of liver in patients who received splenectomy and pericardial blood vessels devascularization in the perioperative period
  • 万方数据
    中华肝胆外科杂志 중화간담외과잡지
    CHINESE JOURNAL OF HEPATOBILIARY SURGERY
    2015年 3期 170-172 ,共3页

    张鹰%李志伟%赵新%肖朝辉%刘虎%余灵祥%张培瑞%张绍庚%林折辉

    장응%리지위%조신%초조휘%류호%여령상%장배서%장소경%림절휘

    门脉高压症%肝硬化%脾切除术%贲门周围血管离断术%肝脏血流动力学%肝功能 門脈高壓癥%肝硬化%脾切除術%賁門週圍血管離斷術%肝髒血流動力學%肝功能
    문맥고압증%간경화%비절제술%분문주위혈관리단술%간장혈류동역학%간공능
    Portal hypertension%Cirrhosis%Splenectomy%Pericardial blood vessels devascularization%Hemodynamics of the liver%Liver function
    目的 探讨脾切除贲门周围血管离断术治疗肝硬化门脉高压症患者短期内肝脏血流动力学及肝功能变化.方法 回顾性分析2013年1月至2013年6月在我院行脾切除贲门血管离断术的39例肝硬化门脉高压患者的术前及术后相关数据.术中采用玻璃管水柱法测量术前及术后自由门静脉压力(FPP).应用超声多普勒分别检测手术前后门静脉血流量(PVF)、肝动脉血流量(HAF).血液生化检查监测术前术后肝功能的变化.结果 本组行脾切断流术的肝硬化门脉高压症患者共39例.FPP由术前的(34.1±0.5)cmH2O(1 cmH2O=0.098 kPa)降至术后的(25.8±0.8)cmH2O (P ＜0.05);PVF由术前的(1 389.5±89.2) ml/min减少至术后的(875.6±76.8)ml/min(P＜0.05);HAF由术前的(586.2±61.8)ml/min增加至术后的(894.1 ±72.9) ml/min(P＜0.05).手术前后肝功Child A级率皆为100％,手术前后肝功无明显差异.结论 脾切除贲门周围血管离断术后患者短期内门脉压力降低,血流量减少.肝动脉血流量增加.手术本身对患者肝脏功能没有显著影响.
    목적 탐토비절제분문주위혈관리단술치료간경화문맥고압증환자단기내간장혈류동역학급간공능변화.방법 회고성분석2013년1월지2013년6월재아원행비절제분문혈관리단술적39례간경화문맥고압환자적술전급술후상관수거.술중채용파리관수주법측량술전급술후자유문정맥압력(FPP).응용초성다보륵분별검측수술전후문정맥혈류량(PVF)、간동맥혈류량(HAF).혈액생화검사감측술전술후간공능적변화.결과 본조행비절단류술적간경화문맥고압증환자공39례.FPP유술전적(34.1±0.5)cmH2O(1 cmH2O=0.098 kPa)강지술후적(25.8±0.8)cmH2O (P ＜0.05);PVF유술전적(1 389.5±89.2) ml/min감소지술후적(875.6±76.8)ml/min(P＜0.05);HAF유술전적(586.2±61.8)ml/min증가지술후적(894.1 ±72.9) ml/min(P＜0.05).수술전후간공Child A급솔개위100％,수술전후간공무명현차이.결론 비절제분문주위혈관리단술후환자단기내문맥압력강저,혈류량감소.간동맥혈류량증가.수술본신대환자간장공능몰유현저영향.
    Objective To investigate the changes in liver function and in haemodynamics of the liver in patients with cirrhosis and portal hypertension who underwent splenectomy and pericardial devascularization.Methods Patients with cirrhosis and portal hypertension treated in our hospital from January 2013 to June 2013 were enrolled into this study.The clinical data were analyzed retrospectively.Results 39 patients with cirrhosis and portal hypertension underwent splenectomy and pericardial devascularization.The portal venous flow (PVF) and the free portal vein pressure (FPP) decreased (1 389.5 ± 89.2 vs 875.6 ± 76.8 ml/min,34.1 ±0.5 vs 25.8 ±0.8 cmH2O (1 cmH2O =0.098 kPa),respectively) and the hepatic arterial flow (HAF) increased (586.2 ±61.8 vs 894.1 ±72.9 ml/min) after the operation.The proportion of patients with Child Pugh class A was the same before and after the operation.Conclusion For patients who underwent splenectomy and pericardial devascularization,the liver function were stable and the free portal pressure and the portal vein flow decreased,while the hepatic arterial flow increased in the perioperative period.
    원문보기 원문다운로드 사이트로이동
저자의 최근 논문