CAJ | 학술논문

目的探讨氟代脱氧葡萄糖(18 F-FDG)正电子发射计算机断层显像(PET)/CT对肝门部胆管癌患者的术前评估价值.方法回顾性分析复旦大学附属中山医院30例术前PET/CT诊断为肝门部胆管癌患者的临床资料.统计分析PET/CT对肝门部胆管癌肿瘤定性、淋巴结转移和远处转移的诊断价值,以及不同肿瘤分期之间最大标准摄取值(SUVmax)的差异.结果 30例患者中14例(46.7％)行根治性切除术,16例(53.3％)行姑息性手术或经皮经肝胆汁引流(PTBD)术.4例(13.3％)经手术诊断为胆囊管癌侵犯肝门部.PET/CT对肝门部胆管癌原发肿瘤定性诊断的敏感度和特异度为100％和0,诊断淋巴结转移的敏感度和特异度为62.5％和90.0％,诊断远处转移的敏感度和特异度为66.7％和85.0％.不同TNM分期肿瘤组织SUVmax值差异无统计学意义(P＞0.05).结论 18F-FDGPET/CT对术前评估肝门部胆管癌是否发生淋巴结转移和远处转移具有重要临床价值,可以使部分患者避免不必要的手术探查;不同分期的肿瘤SUVmax值差异无统计学意义.
목적 탐토불대탈양포도당(18 F-FDG)정전자발사계산궤단층현상(PET)/CT대간문부담관암환자적술전평고개치.방법 회고성분석복단대학부속중산의원30례술전PET/CT진단위간문부담관암환자적림상자료.통계분석PET/CT대간문부담관암종류정성、림파결전이화원처전이적진단개치,이급불동종류분기지간최대표준섭취치(SUVmax)적차이.결과 30례환자중14례(46.7％)행근치성절제술,16례(53.3％)행고식성수술혹경피경간담즙인류(PTBD)술.4례(13.3％)경수술진단위담낭관암침범간문부.PET/CT대간문부담관암원발종류정성진단적민감도화특이도위100％화0,진단림파결전이적민감도화특이도위62.5％화90.0％,진단원처전이적민감도화특이도위66.7％화85.0％.불동TNM분기종류조직SUVmax치차이무통계학의의(P＞0.05).결론 18F-FDGPET/CT대술전평고간문부담관암시부발생림파결전이화원처전이구유중요림상개치,가이사부분환자피면불필요적수술탐사;불동분기적종류SUVmax치차이무통계학의의.
Objective To study the value of 18F-FDG PET/CT in the staging of hilar cholangiocarcinoma.Methods A retrospective study was conducted on 30 patients with hilar cholangiocarcinoma who were evaluated with PET/CT in Zhongshan Hospital,Fudan University.The study analyzed the operative and pathological results in each patient for tumor-node-metastasis staging and the SUVmax value.Results 14(46.7％) patients underwent radical surgery,and 16(53.3％) palliative operation or PTBD treatment.4 (13.3％) patients were shown to have a cystic duct carcinoma which infiltrated the hilum.The sensitivity and specificity in the detection of tumor,regional lymph node metastases and distant metastases were 100％ and 0％,62.5％ and 90.0％,66.7％ and 85.0％ respectively.The SUVmax value in the primary tumor was not significantly associated with the tumor-node-metastasis staging (P ＞ 0.05).Conclusions 18 F-FDG PET/CT imaging was useful in the detection of lymph node and distant metastasis in hilar cholangiocarcinoma,and helped some patients to avoid unnecessary surgical exploration.The SUVmax value had no significant association with tumor staging.