CAJ | 학술논문

目的：探讨孟鲁司特钠治疗小儿咳嗽变异性哮喘的临床疗效。方法将我院2010年4月至2013年8月收治的咳嗽变异性哮喘患儿80例作为研究对象，按其治疗方法分为两组，每组40例，观察组患儿给予孟鲁司特钠口服治疗，对照组患儿给予沙美特罗替卡松粉吸入剂治疗。比较两组患儿临床效果及最大呼气峰流速变化情况。结果观察组患儿总有效率为95.0%，明显高于对照组的80.0%，差异有统计学意义（P＜0.05）；两组患儿治疗前后最大呼气峰流速变化比较，差异无统计学意义（P＞0.05）。结论孟鲁司特钠治疗小儿咳嗽变异性哮喘临床效果明显。
목적：탐토맹로사특납치료소인해수변이성효천적림상료효。방법장아원2010년4월지2013년8월수치적해수변이성효천환인80례작위연구대상，안기치료방법분위량조，매조40례，관찰조환인급여맹로사특납구복치료，대조조환인급여사미특라체잡송분흡입제치료。비교량조환인림상효과급최대호기봉류속변화정황。결과관찰조환인총유효솔위95.0%，명현고우대조조적80.0%，차이유통계학의의（P＜0.05）；량조환인치료전후최대호기봉류속변화비교，차이무통계학의의（P＞0.05）。결론맹로사특납치료소인해수변이성효천림상효과명현。
Objective To investigate the clinical efficacy of montelukast sodium in treatment of children with cough variant asthma.Methods In our hospital from 2010 April to 2013 August were analyzed with cough variant asthma in 80 cases as the object of study,divided into two groups according to the treatment methods,40 cases in each group,the observation group were given montelukast oral therapy,the control group were given the Shah Mette Lo and fluticasone propionate powder for inhalation therapy.Comparison of the clinical effects of two groups and peak expiratory flow changes.Results The observation group with total effective rate was 95.0%,significantly higher than 80.0% in the control group,the difference was statisticaly significant(P<0.05);comparison of maximum peak expiratory flow changes before and after treatment in two groups,no significant difference(P>0.05).Conclusion Montelukast sodium in the treatment of children with cough variant asthma clinical effect is obvious.