CAJ | 학술논문

目的：评价卡前列甲酯栓与米索前列醇预防产后出血的临床效果及预防用药成本。方法选取正常足月妊娠阴道分娩患者126例为研究对象，完全随机分为观察1组、观察2组和对照组，分别给予卡前列甲酯栓、米索前列醇、缩宫素静脉滴注。比较3组患者产后2 h、产后1 d的出血量以及第三产程耗时、收缩压和舒张压情况。结果观察1组与观察2组患者的第三产程耗时及产后2 h、产后1 d的出血量均明显优于对照组，差异均有统计学意义（均P＜0.05）；3组患者的收缩压和舒张压比较，差异无统计学意义（P＞0.05）。观察2组患者的成本比观察1组低，而从增量成本-效果比（△C/△E）来看，若多获得一个效果单位，观察1组要比观察2组多花费36.30元。结论在对产妇实施预防出血和治疗过程中，卡前列甲酯栓的运用可以提高临床预防和治疗的有效性，可减少患者产后出血量，缩短第三产程，稳定收缩压和舒张压，经济条件较差的患者可用米索前列醇代替。
목적：평개잡전렬갑지전여미색전렬순예방산후출혈적림상효과급예방용약성본。방법선취정상족월임신음도분면환자126례위연구대상，완전수궤분위관찰1조、관찰2조화대조조，분별급여잡전렬갑지전、미색전렬순、축궁소정맥적주。비교3조환자산후2 h、산후1 d적출혈량이급제삼산정모시、수축압화서장압정황。결과관찰1조여관찰2조환자적제삼산정모시급산후2 h、산후1 d적출혈량균명현우우대조조，차이균유통계학의의（균P＜0.05）；3조환자적수축압화서장압비교，차이무통계학의의（P＞0.05）。관찰2조환자적성본비관찰1조저，이종증량성본-효과비（△C/△E）래간，약다획득일개효과단위，관찰1조요비관찰2조다화비36.30원。결론재대산부실시예방출혈화치료과정중，잡전렬갑지전적운용가이제고림상예방화치료적유효성，가감소환자산후출혈량，축단제삼산정，은정수축압화서장압，경제조건교차적환자가용미색전렬순대체。
Objective To card forefront methylate suppositories and clinical effect of misoprostol on prevention of postpartum hemorrhage were compared and the prevention of drug costs.Methods To select normal ful-term pregnancy vaginal delivery in 126 cases as the research object,randomly divided into the observation group 1,observation group 2 and control group,were given Carboprost Methylate Suppositorites,misoprostol,oxytocin intravenous drip.Comparison of the three groups of patients postpartum 2 h,1 d postpartum hemorrhage and the third stage of labor consuming,systolic and diastolic blood pressure situations.Results Observed a group and observed two groups of patients and postpartum third stage takes 2 h,1 d postpartum hemorrhage volume was significantly better than the control group,the difference was statisticaly significant(P<0.05);the three groups of patients with systolic and diastolic blood pressure,the difference was not statisticaly significant(P>0.05).2 groups were observed in patients with low cost than observed in the 1 groups,and the incremental cost-effectiveness ratio(delta C/Delta E),if get an effect unit,were observed in the 1 groups were observed in the 2 groups spend more than 36.30 yuan. Conclusion In the parturient bleeding prevention and treatment process,the use of Carboprost Methylate Suppositorites can improve the effectiveness of clinical prevention and treatment of patients,reduce the amount of postpartum hemorrhage,shorten the third stage of labor,improve the systolic and diastolic blood pressure,in patients with poor economic conditions available meters cable forefront alcohol instead of.